eISSN: 1897-4309
ISSN: 1428-2526
Contemporary Oncology/Współczesna Onkologia
Current issue Archive Manuscripts accepted About the journal Supplements Addendum Special Issues Editorial board Journal's reviewers Abstracting and indexing Subscription Contact Instructions for authors Ethical standards and procedures
SCImago Journal & Country Rank
3/2021
vol. 25
 
Share:
Share:
more
 
 
abstract:
Original paper

Comparison of positron emission tomography with computed tomography examination with histopathological assessment of pelvic lymph nodes in patients with cervical cancer treated surgically

Kamila Kaźmierczak
1
,
Witold Cholewiński
2, 3
,
Błażej Nowakowski
1

1.
Surgical, Oncological and Endoscopic Gynaecology Department, Greater Poland Cancer Centre, Poznań, Poland
2.
Electroradiology Department, Poznan University of Medical Sciens, Poznań, Poland
3.
Nuclear Medicine Department, Greater Poland Cancer Center, Poznań, Poland
Contemp Oncol (Pozn) 2021; 25 (3): 160–167
Online publish date: 2021/09/20
View full text
Get citation
ENW
EndNote
BIB
JabRef, Mendeley
RIS
Papers, Reference Manager, RefWorks, Zotero
AMA
APA
Chicago
Harvard
MLA
Vancouver
 
Introduction
According to the literature, fluor-18-fluorodeoxyglucose positron emission tomography with computed tomography (18F-FDG-PET-CT) is the most effective technique for the examination and detection of metastases in the lymph nodes in patients with cervical cancer. This study aimed to compare the diagnostic value of the preoperative evaluation using 18F-FDG-PET-CT with a histopathological examination of the lymph nodes removed during radical hysterectomy and pelvic lymph node dissection in patients with cervical cancer.

Material and methods
Retrospective analysis covered the medical records of 42 patients with cervical cancer (stage IA–IB according to International Federation of Gynaecology and Obstetrics 2009) treated with radical Piver type III hysterectomy and pelvic lymph node dissection. The preoperative diagnosis was made using a PET/CT examination.

Results
The result of the 18F-FDG-PET-CT examination highlighted a suspicion of lymph node metastases in 13 patients (31%). The histopathological examination confirmed this in 12 patients (29%). Metastatic lymph nodes were correctly diagnosed using 18F-FDG-PET-CT in 8 out of the 12 cases confirmed by the histopathological examination. In the patient-based study, sensitivity, specificity, positive predictive value, negative predictive value and accuracy were 66.8%, 83.3%, 61.5%, 86.2 % and 78.6%, respectively.

Conclusions
We confirmed the usefulness of PET in the preoperative assessment of cervical cancer advancement, especially in correlation with the new 2018 International Federation of Gynaecology and Obstetrics staging system.

keywords:

cervical cancer, lymph node metastases, positron emission tomography

Quick links
© 2021 Termedia Sp. z o.o. All rights reserved.
Developed by Bentus.