Diabetic foot syndrome (DFS) is an external symptom of diabetes mellitus that has been ongoing for many years, usually uncontrolled. Systemic treatment must be carried out in parallel with local treatment. The basic element of the therapy is a diagnosis, followed by implementation of causal treatment and proper local management. Because of the increased risk of malnutrition in this group of patients, many studies also indicate the need to implement nutritional treatment. Therefore, in the comprehensive treatment of a patient with DFS, it is also advisable to educate the patient and their family about nutrition and encourage them to choose better nutritional options. This paper presents 2 case reports of patients with DFS in whom nutritional intervention was implemented.