Introduction

The development of ventricular tachycardia (VT) has been shown to be associated with depolarization-repolarization parameters. However, the effect of radiofrequency ablation (RFA) applied for VT on depolarization-repolarization parameters remains unknown.

Aim

This study aimed to investigate changes in measurable depolarization-repolarization parameters following successful RFA in patients with ischemia-induced VT.

Material and methods

Ninety-six patients with ischemic cardiomyopathy who underwent successful RFA for VT between 2018 and 2025 were included. Twelve-lead electrocardiograms (ECGs) were recorded before and after (72 h) the RFA. From both ECGs, PR and QRS durations, QT, corrected QT interval (QTc), Tp–Te intervals, Tp–Te/QT ratio, and QRS–T angle were measured. In addition, left ventricular ejection fraction (LVEF) was measured before and after RFA. Early changes in ECG parameters and LVEF due to RFA were evaluated.

Results

The mean age of the study population was 65.8 ±10.6 years, and 83% of the patients were male. Analysis of ECG parameters showed significant differences before and after VT ablation in QT, QTc, Tp–Te intervals, Tp–Te/QT ratio, and QRS–T angle (p < 0.001 for all). QT interval (426 ±33 vs. 409 ±31 ms), QTc interval (441 ±18 vs. 424 ±17 ms), Tp–Te interval (89 ±16 vs. 80 ±16 ms), Tp–Te/QT ratio (0.21 ±0.04 vs. 0.20 ±0.04), and QRS–T angle (93 ±51º vs. 72 ±45º) were all reduced after RFA. There was no significant change in LVEF before and after RFA (33.6 ±9.8 vs.34.1 ±8.5, Z = –1.356, p = 0.195).

Conclusions

Our findings demonstrated that successful RFA therapy in patients with ischemia-induced VT has favorable early effects on ventricular depolarization-repolarization parameters. This information provides a novel and important contribution to the literature on VT ablation.