Efficacy of sonic irrigation activation approaches in managing post endodontic pain: a randomized clinical trial

Nishtha Patel; Kailash Attur; Shalini Aggarwal; Shylaja Attur; Pooja Kesharani; Nikunjbhai Sorathiya

doi:10.5114/jos.2026.160124

eISSN: 2299-551X
ISSN: 0011-4553

Journal of Stomatology

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abstract:

Original paper

Efficacy of sonic irrigation activation approaches in managing post endodontic pain: a randomized clinical trial

Nishtha Kiran Patel

¹

,

Kailash Attur

²

,

Shalini Aggarwal

³

,

Shylaja K. Attur

⁴

,

Pooja R. Kesharani

¹

,

Nikunjbhai H. Sorathiya

¹

Department of Conservative Dentistry and Endodontics, College of Dental Science and Research Centre, Ahmedabad, Gujarat, India
Department of Conservative Dentistry and Endodontics, Narsinhbhai Patel Dental College and Hospital, Gujarat, India
Department of Conservative Dentistry and Endodontics, Dr. D. Y. Patil Dental College and Hospital, Pimpri, Pune, India
Department of Oral Pathology, Narsinhbhai Patel Dental College and Hospital, Gujarat, India

J Stoma 2026; 79, 1: 31-37

DOI: https://doi.org/10.5114/jos.2026.160124

Online publish date: 2026/03/15

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Introduction
Postoperative pain after endodontic treatment negatively impacts patients’ quality of life. Therefore, minimizing post endodontic pain (PEP) is a key goal for clinicians, as it is both undesirable and reflect the success of treatment. The study aimed to evaluate PEP following single-visit root canal treatment, using ProTaper Next (PTN) and TruNatomy (TN) file systems in combination with side-vented needle (SV) and EndoActivator (EA) irrigation techniques.

Material and methods
Based on specific intraoral examination, 140 individuals were selected and distributed into 4 different criteria groups: Group 1 (PTN-SV), group 2 (PTN-EA), group 3 (TN-SV), and group 4 (TN-EA). To avoid discomfort during treatment, local anesthesia was administrated. PEP potency was observed and analyzed using visual analogue scale (VAS) at 6, 12, 24, and 48 hours posttreatment intervals. Data were statistically analyzed via SPSS version 20.0 software, with a significance level set at 0.05.

Results
At 6 and 12 hours, TN-EA showed the lowest PEP scores compared with other groups, and a statistically significant difference was observed. However, at 24 and 48 hours, no statistically significant differences were noted among all groups.

Conclusions
The pain potency after endodontic therapy was minimal when using the TN file system combined with EA irrigation, indicating its effectiveness in reducing posttreatment pain.

keywords:

Efficacy of sonic irrigation activation approaches in managing post endodontic pain: a randomized clinical trial

Nishtha Kiran Patel 1 , Kailash Attur 2 , Shalini Aggarwal 3 , Shylaja K. Attur 4 , Pooja R. Kesharani 1 , Nikunjbhai H. Sorathiya 1

EndoActivator, post endodontic pain, ProTaper Next, TruNatomy, visual analogue scale

Nishtha Kiran Patel

¹

,

Kailash Attur

²

,

Shalini Aggarwal

³

,

Shylaja K. Attur

⁴

,

Pooja R. Kesharani

¹

,

Nikunjbhai H. Sorathiya

¹