eISSN: 2299-0038
ISSN: 1643-8876
Menopause Review/Przegląd Menopauzalny
Current issue Archive Manuscripts accepted About the journal Special Issues Editorial board Abstracting and indexing Subscription Contact Instructions for authors Ethical standards and procedures

SCImago Journal & Country Rank
 
2/2006
vol. 5
 
Share:
Share:
more
 
 
abstract:

Endometrial hyperplasia: efficacy of treatment with vaginal tablet containing natural micronized progesterone

Beata Szymańska
,
Agnieszka Gardyszewska
,
Joanna Pabich
,
Krzysztof Czajkowski

Prz Menopauz 2006; 2: 75–79
Online publish date: 2006/05/12
View full text
Get citation
ENW
EndNote
BIB
JabRef, Mendeley
RIS
Papers, Reference Manager, RefWorks, Zotero
AMA
APA
Chicago
Harvard
MLA
Vancouver
 

Objectives:
The aim of this study was to evaluate the efficiency of treatment with a vaginal tablet containing natural micronized progesterone in patients with endometrial hyperplasia.
Material and methods:
Forty one patients with endometrial hyperplasia were enrolled in this trial; 38 patients have been presented simple hyperplasia, 3 complex hyperplasia. All patients were treated with vaginal tablets containing micronized progesterone 2 x 100 mg/day for 3 months. During first month of treatment 6 patients were bleeding and were excluded from the study. 35 patients finished treatment.
Results:
We observed a total of 33 complete regressions (94%). Recurrence of simple hyperplasia occurred in 1 patient (3%), and in 1 patient (3%) we noticed progresion from simple to complex hyperplasia. 7 patients (17%) had irregular spotting, 4 (9,8%) had vaginal discomfort.
Conclusions:
Vaginal administration of natural micronized progesterone seems to be effective and safe therapy of benign endometrial hyperplasia, particularly indicated in women also affected by metabolic disorders.
keywords:

progesterone, endometrial hyperplasia, vaginal administration

Quick links
© 2021 Termedia Sp. z o.o. All rights reserved.
Developed by Bentus.