Advances in Interventional Cardiology
eISSN: 1897-4295
ISSN: 1734-9338
Advances in Interventional Cardiology/Postępy w Kardiologii Interwencyjnej
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Enhancing reperfusion in a large thrombus burden STEMI patient with intracoronary thrombolysis: back to the future?

George Kassimis
1
,
Georgios Zormpas
1
,
Athina Nasoufidou
1
,
Konstantinos C. Theodoropoulos
2
,
Antonios Ziakas
2
,
Nikolaos Fragakis
1

  1. 2nd Cardiology Department, Hippokration Hospital, Medical School, Aristotle University of Thessaloniki, Greece
  2. 1st Cardiology Department, AHEPA University Hospital, Aristotle University of Thessaloniki, Greece
Adv Interv Cardiol
DOI: https://doi.org/10.5114/aic.2025.156710
Online publish date: 2025/12/03
Article file
- enhancing reperfusion.pdf  [0.26 MB]
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1. De Maria GL, Patel N, Kassimis G, Banning AP. Spontaneous and procedural plaque embolisation in native coronary arteries: pathophysiology, diagnosis, and prevention. Scientifica 2013; 2013: 364247.
2. Byrne RA, Rossello X, Coughlan JJ, et al. 2023 ESC Guidelines for the management of acute coronary syndromes. Eur Heart J 2023; 44: 3720-826.
3. Sianos G, Papafaklis MI, Daemen J, et al. Angiographic stent thrombosis after routine use of drug-eluting stents in ST-segment elevation myocardial infarction: the importance of thrombus burden. J Am Coll Cardiol 2007; 50: 573-83.
4. Jolly SS, Cairns JA, Lavi S, et al. Thrombus aspiration in patients with high thrombus burden in the TOTAL trial. J Am Coll Cardiol 2018; 72: 1589-96.
5. Alexiou S, Patoulias D, Theodoropoulos KC, et al. Intracoronary thrombolysis in ST-segment elevation myocardial infarction patients undergoing primary percutaneous coronary intervention: an updated meta-analysis of randomized controlled trials. Cardiovasc Drugs Ther 2024; 38: 335-46.
6. Serafin K, Zimoch W, Kuliczkowski W, Reczuch K. Conservative treatment of anterior ST-segment elevation myocardial infarction with a large thrombus burden in the left main coronary artery. Adv Interv Cardiol 2022; 18: 311-3.
7. Feng X, Liu T. Identification and management strategies for intracoronary high thrombus burden in patients with STEMI: a practical experience and literature review. Rev Cardiovasc Med 2025; 26: 37466.
Copyright: © 2025 Termedia Sp. z o. o. This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) License (http://creativecommons.org/licenses/by-nc-sa/4.0/), allowing third parties to copy and redistribute the material in any medium or format and to remix, transform, and build upon the material, provided the original work is properly cited and states its license.
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