Examining the effect of HPV vaccination in order to prevent cervical cancer – a systematic review

Nasim Alinezhad

doi:10.5114/.2025.151338

eISSN: 2084-9850
ISSN: 1897-3116

Pielęgniarstwo Chirurgiczne i Angiologiczne/Surgical and Vascular Nursing

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vol. 19

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abstract:

Review paper

Examining the effect of HPV vaccination in order to prevent cervical cancer – a systematic review

Nasim Alinezhad

¹

Ardabil University of Medical Sciences, Ardabil, Iran

Pielęgniarstwo Chirurgiczne i Angiologiczne 2025; 19(1): 8-13

DOI: https://doi.org/10.5114/.2025.151338

Online publish date: 2025/05/26

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The present study investigated the effect of human papillomavirus (HPV) vaccination in preventing cervical cancer. In the current study, 63 articles published in 2010–2024 were reviewed with keywords including “cervical cancer”, “HPV”, and “uterine cancer” in PubMed, Scopus, Science Direct, Elsevier and Wiley databases. The risk ratio of cervical cancer screening was 1.15 times (HR = 1.15; 95% CI: 0.18–2.21) higher among HPV-vaccinated women than unvaccinated women. Women with two doses of HPV vaccine were more likely to initiate screening (HR = 1.66; 95% CI: 0.43– 2.89; I² = 0). Receiving at least one dose of HPV vaccination was associated with a higher rate of cervical cancer screening, which reduces the risk of cervical cancer by increasing the number of doses to two and three doses, and with more timely screening, cervical cancer can be detected.

keywords:

Examining the effect of HPV vaccination in order to prevent cervical cancer – a systematic review

Nasim Alinezhad 1

cervical cancer, uterine cancer, HPV

Nasim Alinezhad

¹