eISSN: 2299-0038
ISSN: 1643-8876
Menopause Review/Przegląd Menopauzalny
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5/2005
vol. 4
 
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abstract:

Genetic polymorphisms in coagulation and fibrinolysis systems versus thromboembolic risk of estrogen-progestin therapies in women

Grzegorz Stachowiak
,
Tomasz Stetkiewicz
,
Sławomir Jędrzejczyk
,
Anna Sobczuk
,
Andrzej Makuła
,
Tomasz Pertyński

Prz Menopauz 2005; 5: 59–64
Online publish date: 2005/11/02
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This article is a survey of some genetic polymorphisms present in coagulation and fibrinolysis systems, with potential influence on the thromboembolic risk of oral contraception and hormone therapy of the menopausal period. It seems that these thrombophilic anomalies are responsible in part for the increased thrombotic risk being characteristic in particular for the first year of sex steroid administration in women.
keywords:

genetic polymorphisms, menopause, coagulation, fibrinolysis, hormone therapy, oral contraception
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