Introduction. Hypodontia is malformation of
dentition characterized by deficit of one to six tooth
germs. Hypodontia of upper lateral incisors occurs
in 27% of cases and is ranked second with regard
to incidence. Etiology of hypodontia is complex
and results from interaction of various factors in
the process of formation and development of tooth
germs. Hypodontia of upper lateral incisors may
be genetically, phylogenetically, neurogenically,
environmentally conditioned, or may result from
premature ossification of sella turcica. Complex
etiology of hypodontia is reflected in complex
treatment protocols of this condition. Aim of the
study. To perform systematic literature review of
therapeutic procedures regarding hypodontia of upper
lateral incisors in adults. Material and methods. The
data were collected with the use of Medline, PubMed,
Cochrane Library and available library resources.
The search terms were: hypodontia, interdisciplinary,
orthodontic and prosthetic treatment of hypodontia,
canine mesialization, implant, mini implant and fixed
prosthesis. Conclusion. On the basis of obtained
information it must be stated that rehabilitation of
adult patients with diagnosed hypodontia of upper
lateral incisors is a difficult clinical procedure.
Therapeutic procedures are complex and require
interdisciplinary approach, which takes into account
dentition, patients’ preferences, age as well as type
of future prosthetic restoration. Treating patients