1. Lischner MW, Alexander JF, Galambos JT. Natural history of alcoholic hepatitis. I. The acute disease. Am J Dig Dis 1971; 16: 481-494.
2.
Lucey MR, Mathurin P, Morgan TR. Alcoholic hepatitis. N Engl J Med 2009; 360: 2758-2769.
3.
Mendenhall CL. Alcoholic hepatitis. Clin Gastroenterol 1981; 10: 417-441.
4.
Morgan TR. Management of alcoholic hepatitis. Gastroenterol Hepatol 2007; 3: 97-99.
5.
Hall P, Cash J. What is the real function of the liver ‘function’ tests? Ulster Med J 2012; 81: 30-36.
6.
Torruellas C, French SW, Medici V. Diagnosis of alcoholic liver disease. World J Gastroenterol 2014; 20: 11684-11699.
7.
Li CP, Lee FY, Hwang SJ, et al. Spider angiomas in patients with liver cirrhosis: role of vascular endothelial growth factor and basic fibroblast growth factor. World J Gastroenterol 2003; 9: 2832-2835.
8.
Garcia-Tsao G, Bosch J. Varices and variceal hemorrhage in cirrhosis: A New View of an old problem. Clin Gastroenterol Hepatol 2015; 13: 2109-2117.
9.
Iruzubieta P, Terán Á, Crespo J, Fábrega E. Vitamin D deficiency in chronic liver disease. World J Hepatol 2014; 6: 901-915.
10.
Elangovan H, Chahal S, Gunton JE. Vitamin D in liver disease: Current evidence and potential directions. Biochim Biophys Acta Mol Basis Dis 2017; 1863: 907-916.
11.
Lee SM, Jun DW, Cho YK, Jang KS. Vitamin D deficiency in non-alcoholic fatty liver disease: The chicken or the egg? Clin Nutr 2017; 36: 191-197.
12.
Kucukazman M, Ata N, Dal K, et al. The association of vitamin D deficiency with non-alcoholic fatty liver disease. Clinics (Sao Paulo) 2014; 69: 542-546.
13.
Konstantakis C, Tselekouni P, Kalafateli M, Triantos C. Vitamin D deficiency in patients with liver cirrhosis. Ann Gastroenterol 2016; 29: 297-306.
14.
Testino G, Leone S, Fagoonee S. Alcoholic liver disease and vitamin D deficiency. Minerva Med 2018; 109: 341-343.
15.
Long RG, Skinner RK, Wills MR, Sherlock S. Serum-25-hydroxy-vitamin-D in untreated parenchymal and cholestatic liver disease. Lancet 1976; 2: 650-652.
16.
Savic Z, Damjanov D, Curic N, et al. Vitamin D status, bone metabolism and bone mass in patients with alcoholic liver cirrhosis. Bratisl Lek Listy 2014; 115: 573-578.
17.
Arteh J, Narra S, Nair S. Prevalence of vitamin D deficiency in chronic liver disease. Dig Dis Sci 2010; 55: 2624-2628.
18.
Barchetta I, Carotti S, Labbadia G, et al. Liver vitamin D receptor, CYP2R1, and CYP27A1 expression: relationship with liver histology and vitamin D3 levels in patients with nonalcoholic steatohepatitis or hepatitis C virus. Hepatology 2012; 56: 2180-2187.
19.
Dong B, Zhou Y, Wang W, et al. Vitamin D receptor activation in liver macrophages ameliorates hepatic inflammation, steatosis, and insulin resistance in mice. Hepatology 2020; 71: 1559-1574.
20.
Stokes CS, Krawczyk M, Reichel C, et al. Vitamin D deficiency is associated with mortality in patients with advanced liver cirrhosis. Eur J Clin Invest 2014; 44: 176-183.
21.
Abramovitch S, Sharvit E, Weisman Y, et al. Vitamin D inhibits development of liver fibrosis in an animal model but cannot ameliorate established cirrhosis. Am J Physiol Gastrointest Liver Physiol 2015; 308: G112-120.
22.
Kawaratani H, Moriya K, Namisaki T, et al. Therapeutic strategies for alcoholic liver disease: Focusing on inflammation and fibrosis (Review). Int J Mol Med 2017; 40: 263-270.
23.
Astakhin AV, Levitan BN, Afanas’ev SS, et al. Tumor necrosis factor-alpha and interleukin-4 in the blood sera of chronic hepatitis patients. Zh Mikrobiol Epidemiol Immunobiol 2004; 2: 46-50.
24.
Tilg H, Moschen AR, Szabo G. Interleukin-1 and inflammasomes in alcoholic liver disease/acute alcoholic hepatitis and nonalcoholic fatty liver disease/nonalcoholic steatohepatitis. Hepatology 2016; 64: 955-965.
25.
Tung KH, Huang YS, Yang KC, et al. Serum interleukin-12 levels in alcoholic liver disease. J Chin Med Assoc 2010; 73: 67-71.
26.
Yamauchi T, Kamon J, Ito Y, et al. Cloning of adiponectin receptors that mediate antidiabetic metabolic effects. Nature 2003; 423: 762-769.
27.
Tilg H, Moschen AR. Adipocytokines: mediators linking adipose tissue, inflammation and immunity. Nat Rev Immunol 2006; 6: 772-783.
28.
Yu Y, Venners SA, Wang B, et al. Association of central adiposity with prediabetes and decreased insulin sensitivity in rural Chinese normal-weight and overweight women. Metabolism 2010; 59: 1047-1053.
29.
Abbott Laboratories: Brochure: IA_09_23864/v1, AK2117-10 No. In.; 2010.
30.
Grunkemeier GL, Wu Y. Bootstrap resampling methods: something for nothing? Ann Thorac Surg 2004; 77: 1142-1144.
31.
Spearman Rank Correlation Coefficient. In: The Concise Encyclopedia of Statistics. edn. Springer New York, New York, NY 2008; 502-505.
32.
Li G, Wu W, Zhang X, et al. Serum levels of tumor necrosis factor alpha in patients with IgA nephropathy are closely associated with disease severity. BMC Nephrol 2018; 19: 326.
33.
Zhang J, Bai C. Elevated serum interleukin-8 level as a preferable biomarker for identifying uncontrolled asthma and glucocorticosteroid responsiveness. Tanaffos 2017; 16: 260-269.
34.
Tomasiuk R, Zubrzycki IZ, Wiacek M. Age-dependent changes in fat- and water-soluble vitamins-National Health and Nutrition Examination Surveys study. Front Med 2022; 9: 907067.
35.
O’Neill CM, Lu C, Corbin KL, et al. Circulating levels of IL-1B +IL-6 cause ER stress and dysfunction in islets from prediabetic male mice. Endocrinology 2013; 154: 3077-3088.
36.
Said EA, Al-Reesi I, Al-Shizawi N, et al. Defining IL-6 levels in healthy individuals: A meta-analysis. J Med Virol 2021; 93: 3915-3924.
37.
Tokano Y, Morimoto S, Kaneko H, et al. Levels of IL-12 in the sera of patients with systemic lupus erythematosus (SLE) – relation to Th1- and Th2-derived cytokines. Clin Exp Immunol 1999; 116: 169-173.
38.
Chan WSA, Liew CF, Theng CTS, Oon HH. Serum adiponectin levels and their association with cardiometabolic risk factors in patients with psoriasis. Cureus 2020; 12: e8128.
39.
Ohashi K, Pimienta M, Seki E. Alcoholic liver disease: A current molecular and clinical perspective. Liver Res 2018; 2: 161-172.
40.
Rey I, Effendi-Ys R. Association between serum IL-6, IL-10, IL-12, and IL-23 levels and severity of liver cirrhosis. Med Arch 2021; 75: 199-203.
41.
Tomasiuk R, Zubrzycki IZ, Wiacek M. Age-dependent changes in fat- and water-soluble vitamins – NHANES study. Unpublished 2022.
42.
Putz-Bankuti C, Pilz S, Stojakovic T, et al. Association of 25-hydroxyvitamin D levels with liver dysfunction and mortality in chronic liver disease. Liver Int 2012; 32: 845-851.
43.
Damas P, Reuter A, Gysen P, et al. Tumor necrosis factor and interleukin-1 serum levels during severe sepsis in humans. Crit Care Med 1989; 17: 975-978.
44.
El Menyawi M, Fawzy M, Al-Nahas Z, et al. Serum tumor necrosis factor alpha (TNF-α) level in patients with Behçet’s disease: Relation to clinical manifestations and disease activity. Egypt Rheumatol 2014; 36: 139-143.
45.
Mourtzikou A, Alepaki M, Stamouli M, et al. Evaluation of serum levels of IL-6, TNF-α, IL-10, IL-2 and IL-4 in patients with chronic hepatitis. Inmunología 2014; 33: 41-50.
46.
Naveau S, Emilie D, Balian A, et al. Plasma levels of soluble tumor necrosis factor receptors p55 and p75 in patients with alcoholic liver disease of increasing severity. J Hepatol 1998; 28: 778-784.
47.
Neuman MG, Maor Y, Nanau RM, et al. Alcoholic liver disease: Role of cytokines. Biomolecules 2015; 5: 2023-2034.
48.
Sheron N, Bird G, Goka J, et al. Elevated plasma interleukin-6 and increased severity and mortality in alcoholic hepatitis. Clin Exp Immunol 1991; 84: 449-453.
49.
Hong F, Kim WH, Tian Z, et al. Elevated interleukin-6 during ethanol consumption acts as a potential endogenous protective cytokine against ethanol-induced apoptosis in the liver: involvement of induction of Bcl-2 and Bcl-xL proteins. Oncogene 2002; 21: 32-43.
50.
Hill DB, Marsano L, Cohen D, et al. Increased plasma interleukin-6 concentrations in alcoholic hepatitis. J Lab Clin Med 1992; 119: 547-552.
51.
Prystupa A, Kiciński P, Sak J, et al. Proinflammatory cytokines (IL-1α, IL-6) and hepatocyte growth factor in patients with alcoholic liver cirrhosis. Gastroenterol Res Pract 2015; 2015: 532615.
52.
Feng L, Qi Q, Wang P, et al. Serum levels of IL-6, IL-8, and IL-10 are indicators of prognosis in pancreatic cancer. J Int Med Res 2018; 46: 5228-5236.
53.
Huang YS, Chan CY, Wu JC, et al. Serum levels of interleukin-8 in alcoholic liver disease: relationship with disease stage, biochemical parameters and survival. J Hepatol 1996; 24: 377-384.
54.
Ouchi N, Walsh K. Adiponectin as an anti-inflammatory factor. Clin Chim Acta 2007; 380: 24-30.
55.
Laso FJ, Iglesias MC, Lopez A, et al. Increased interleukin-12 serum levels in chronic alcoholism. J Hepatol 1998; 28: 771-777.
56.
Nigro E, Scudiero O, Monaco ML, et al. New insight into adiponectin role in obesity and obesity-related diseases. Biomed Res Int 2014; 2014: 658913-658913.
57.
Suárez-Álvarez K, Solís-Lozano L, Leon-Cabrera S, et al. Serum IL-12 is increased in Mexican obese subjects and associated with low-grade inflammation and obesity-related parameters. Mediators Inflamm 2013; 2013: 967067.
58.
Buechler C, Schaffler A, Johann M, et al. Elevated adiponectin serum levels in patients with chronic alcohol abuse rapidly decline during alcohol withdrawal. J Gastroenterol Hepatol 2009; 24: 558-563.
59.
Kalafateli M, Triantos C, Tsochatzis E, et al. Adipokines levels are associated with the severity of liver disease in patients with alcoholic cirrhosis. World J Gastroenterol 2015; 21: 3020-3029.
60.
Stefan N, Stumvoll M. Adiponectin – its role in metabolism and beyond. Horm Metab Res 2002; 34: 469-474.
61.
Borges MD, Franca EL, Fujimori M, et al. Relationship between proinflammatory cytokines/chemokines and adipokines in serum of young adults with obesity. Endocr Metab Immune Disord Drug Targets 2018; 18: 260-267.
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