Alcohol consumption in the COVID-19 era is a health emergency. Loneliness and social distancing cause alcohol abuse. Alcohol consumption through a continuum during the isolation period has created new cases of alcohol use disorders. To all this, we must add the increased risk of infection and deteriorating symptoms. In fact, it is known that ethanol reduces the activity of adaptive and acquired immunity and promotes the expression of ACE2 receptors. Healthcare institutions are required to inform citizens properly about alcohol-related problems in this emergency period.