Abstract
Stage one adenocarcinoma of uterine cervix in a patient with systemic lupus erythematosus – a clinical case
- Obstetrics and Gynaecology Clinic, Acibadem City Clinic Hospital “Tokuda”, Sofia, Bulgaria
- Department of Gynaecological Oncology, Medical University of Pleven, Bulgaria
- General Surgery Clinic, Acibadem City Clinic Hospital “Tokuda”, Sofia, Bulgaria
- Clinic of Gastroenterology, University Hospital for Active Treatment „Alexandrovska”, Sofia, Bulgaria
Introduction
The systemic lupus erythematosus (SLE) is a comparatively rare chronic autoimmune disease in women of reproductive age, the pathogenesis and therapy of which also conditions the increased risk of development of malignant diseases.
Case report
We present a clinical case of a 38-year-old female patient with lupus and stage 1B1 adenocarcinoma of uterine cervix, in which robotic radical hysterectomy with pelvic lymph node dissection has been successfully performed. The strict primary and secondary prophylaxis for pathological changes of uterine cervix are of essential significance for patients with lupus.
Conclusions
SLE is a chronic autoimmune disease, which is frequently treated with immunosuppressors, and affects most often women in reproductive age. The combination of these conditions is associated with higher risk of infecting with HPV and occurrence of pre-cancer and cancer of uterine cervix. Based on these reasons women with SLE must undergo strict screening follow-up and vaccination against high-risk strains of HPV. In the cases of cancer of uterine cervix diagnosed in initial stage, the striving towards minimal traumatism and better quality of life of patient – and, at the same time, towards achievement of optimal radicality – directs to the choice of minimally invasive operative method such as the robotic surgery.
Keywords
systemic lupus erythematosus, adenocarcinoma of uterine cervix, robotic surgery
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