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3/2011
vol. 10 abstract:
Review paper
Vasomotor symptoms in menopause – diagnostic and treatment
Małgorzata Sobstyl
,
Wiesława Bednarek
,
Joanna Tkaczuk-Włach
,
Jacek Sobstyl
,
Grzegorz Jakiel
Przegląd Menopauzalny 2011; 3: 254–259
Online publish date: 2011/07/04
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Hot flashes and night sweats are common menopausal symptoms, which influence greatly the quality of women’s lives, often by eliminating them from professional or everyday lives. Etiopathogenesis of symptoms has not been fully explained. A great role is attributed to sudden decrease of estrogens, disorders of neurotransmitters and neuromodulators activity such as noradrenalin, dopamine, serotonin and thermoregulation disorders. Estrogen and estrogen-progestogen therapy is recommended as the most effective treatment for vasomotor symptoms. Yet, more and more consideration should be given to selective inhibitors of serotonin and noradrenalin, gabapentin.
keywords:
hot flashes, night sweats, hormonal therapy, menopause |