Abstract
1-2/2025
vol. 20
Case report
Chasing the diagnosis – diagnostic challenges in a patient with psychiatric disorders as the first symptoms of Wilson’s disease
- Oddział Psychiatryczny Męski, Wojewódzki Szpital Zespolony im. Ludwika Rydygiera w Toruniu
Neuropsychiatria i Neuropsychologia 2025; 20, 1–2: 40–45
Online publish date: 2025/04/24
This report presents a case of a 34-year-old patient manifesting psychiatric symptoms, including suicidal thoughts, disorganized behavior, anhedonia, and avolition, which began six months prior to hospitalization. An initial diagnosis of hebephrenic schizophrenia/schizoaffective disorder was made. Due to an atypical clinical presentation, additional laboratory and imaging tests, as well as specialist consultations, were conducted, leading to a diagnosis of Wilson’s disease. Genetic testing was performed to confirm the diagnosis. Treatment with anti-copper agents, antipsychotics, and a tailored diet resulted in the patient’s improvement. This case highlights diagnostic challenges and reviews the newest available American guidelines for diagnosing this condition.
Keywords
Wilson’s disease, schizophrenia, antipsychotic agents, suicidal ideation
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