Consequences of parvovirus B19 infection in women with imminent abortion

Daniela Friedek; Małgorzata Romanik; Zbigniew Chełmicki; Barbara Wiechuła

ISSN: 1231-6407

Ginekologia Praktyczna - - - ARCHIVAL

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5/2003
vol. 11

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abstract:

Consequences of parvovirus B19 infection in women with imminent abortion

Daniela Friedek

,

Małgorzata Romanik

,

Zbigniew Chełmicki

,

Barbara Wiechuła

Gin Prakt 2003, 11, 5, 48-51

Online publish date: 2003/10/16

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Purpose of the study was to determine serologic or genetic markers of parvovirus B19 infection (PV-B19) in women during first trimester of pregnancy and to observe the course of infection and its influence on fetus.

IgM and IgG antibodies against PV-B19 were determined with immunoenzimatic method (BIOMEDICA). The PV-B19 DNA was detected with PCR method and obtained DNA was analyzed with Digene Sharp Signal system.
Our studies shown that abortion frequency in women with PV-B19 infection is 27%, most of them occurred during first trimester of pregnancy. Parvovirus infection in observed pregnant women was in most cases asymptomatic, therefore it may be helpful to diagnose patients towards PV-B19 infection during pregnancy.

keywords:

Consequences of parvovirus B19 infection in women with imminent abortion

Daniela Friedek , Małgorzata Romanik , Zbigniew Chełmicki , Barbara Wiechuła

pregnancy, imminent abortion, Parvovirus B19, ELISA, PCR

Daniela Friedek

,

Małgorzata Romanik

,

Zbigniew Chełmicki

,

Barbara Wiechuła