ISSN: 1428-2526
Contemporary Oncology
SCImago Journal & Country Rank

Effusion to the pleural cavity as the clinical manifestation of the relapse of medulloblastoma – the case report

Maria Bernas, Grzegorz Słomian, Beata Utracka-Hutka, Elżbieta Nowara, Beata Maksymiuk

Współcz Onkol (2005) vol. 9; 2 (69–71)
Medulloblastoma is a rare brain tumor, it affects mainly children and its frequency among adults is less then 1%. Extracranial dissemination is uncommon, but when it happens, the disease spreads to the bones (77%), lymph nodes (33%) and lungs (17%). This can be explained both by anatomical and immunological distinctions of the nervous system and a relatively short overall survival time. In the treatment of medulloblastomas with extracranial dissemination therapeutic benefits may be gained with the use of alkylating agents, alkaloids and cytotoxic antibiotics.
This paper presents a case of a 36-year--old male with cerebellar medulloblastoma treated in December 2000 with radical surgery and susequently with adjuvant postoperative radiotherapy. 3 years after initial treatment, the patient had a relaps in the form to dissemination in the thorax and bones (lung, pleura, thoracic vertebrae, sternum and ribs). Main clinical symptoms included shortness of breath caused by pleural effusion and chest pain due to infiltration of intercostals muscles and rib osteolysis.
The patient was treated with multidrug chemotherapy based on cisplatin, etoposid and ifosfamid. Before the systemic therapy he received short radiotherapy for the pain of the chest wall. After 6 cycles of chemotherapy, significant regression of the tumor and complete disappearance of symptoms was observed. The only side effect of treatment was anaemia, which required blood substitution and the use of erythropoietin.

brain tumors, adults medulloblastoma, extracranial dissemination, pleural effusion, chemotherapy

Featured products
Bates – kieszonkowy przewodnik po badaniu podmiotowym i przedmiotowym
Lynn S. Bickley

prof. dr hab. n. med. Zbigniew Gaciong
dr n. med. Piotr Jędrusik

Format: 108x180
Liczba stron: 432
Oprawa: miękka
Stany nagłe w onkologii. Występowanie i leczenie
pod redakcją Andrzeja W. Szawłowskiego i Grzegorza Wallnera
2 tomy

TOM I - Format: B5, liczba stron: 340, oprawa miękka
cena: 92.00 zł

TOM II - Format: B5, liczba stron: 444, oprawa miękka
cena: 92.00 zł

Cała prawda o e-papierosach

Jean-François Etter, Gérard Mathern

Format: 125x197 mm
Liczba stron: 208
Oprawa: miękka
Kompendium postępowania w nowotworach wątroby
pod redakcją Krzysztofa Simona i Krzysztofa Krzemienieckiego

Format: A5
Liczba stron: 88
Oprawa: miękka
Studenci Medycyny i Farmacji
Portal adresowanych do studentów uczelni medycznych w Polsce i za granicą.
Copyright notice Privacy policy Advertising policy Contact us
Stosujemy się do standardu HONcode dla wiarygodnej informacji zdrowotnej This site complies with the HONcode standard for trustworthy health information: verify here
Created by Bentus
PayU - płatności internetowe