Is the clinical manifestation of anaphylaxis in children influenced by the trigger of reaction?

Izabela Tarczoń; Urszula Jedynak-Wąsowicz; Grzegorz Lis; Tomasz Tomasik; Piotr Brzyski; Ewa Cichocka-Jarosz

doi:10.5114/ada.2020.95650

eISSN: 2299-0046
ISSN: 1642-395X

Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii

Current issue Archive Manuscripts accepted About the journal Editorial board Reviewers Abstracting and indexing Subscription Contact Instructions for authors Publication charge Ethical standards and procedures

Editorial System

Submit your Manuscript

Editorial Policies

Sarajevo Declaration on Integrity and Visibility of Scholarly Publications

5/2021
vol. 38

Send email

Copy url:

abstract:

Original paper

Is the clinical manifestation of anaphylaxis in children influenced by the trigger of reaction?

Izabela Tarczoń

¹

,

Urszula Jedynak-Wąsowicz

²

,

Grzegorz Lis

²

,

Tomasz Tomasik

²

,

Piotr Brzyski

³

,

Ewa Cichocka-Jarosz

²

“Przyladek Zdrowia”, Krakow, Poland
Department of Paediatrics, Jagiellonian University Medical College, Krakow, Poland
“Dziupla” Statistical Analysis, Krakow, Poland

Adv Dermatol Allergol 2021; XXXVIII (5): 788-797

DOI: https://doi.org/10.5114/ada.2020.95650

Online publish date: 2020/06/26

View full text Get citation

EndNote

Papers, Reference Manager, RefWorks, Zotero

AMA

Tarczoń I, Jedynak-Wąsowicz U, Lis G, Tomasik T, Brzyski P, Cichocka-Jarosz E. Is the clinical manifestation of anaphylaxis in children influenced by the trigger of reaction?. Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii. 2021;38(5):788-797. doi:10.5114/ada.2020.95650.

APA

Tarczoń, I., Jedynak-Wąsowicz, U., Lis, G., Tomasik, T., Brzyski, P.,  & Cichocka-Jarosz, E. (2021). Is the clinical manifestation of anaphylaxis in children influenced by the trigger of reaction?. Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii, 38(5), 788-797. https://doi.org/10.5114/ada.2020.95650

Chicago

Tarczoń, Izabela, Urszula Jedynak-Wąsowicz, Grzegorz Lis, Tomasz Tomasik, Piotr Brzyski,  and Ewa Cichocka-Jarosz. 2021. "Is the clinical manifestation of anaphylaxis in children influenced by the trigger of reaction?". Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii 38 (5): 788-797. doi:10.5114/ada.2020.95650.

Harvard

Tarczoń, I., Jedynak-Wąsowicz, U., Lis, G., Tomasik, T., Brzyski, P.,  and Cichocka-Jarosz, E. (2021). Is the clinical manifestation of anaphylaxis in children influenced by the trigger of reaction?. Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii, 38(5), pp.788-797. https://doi.org/10.5114/ada.2020.95650

MLA

Tarczoń, Izabela et al. "Is the clinical manifestation of anaphylaxis in children influenced by the trigger of reaction?." Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii, vol. 38, no. 5, 2021, pp. 788-797. doi:10.5114/ada.2020.95650.

Vancouver

Tarczoń I, Jedynak-Wąsowicz U, Lis G, Tomasik T, Brzyski P, Cichocka-Jarosz E. Is the clinical manifestation of anaphylaxis in children influenced by the trigger of reaction?. Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii. 2021;38(5):788-797. doi:10.5114/ada.2020.95650.

Introduction
The number of anaphylaxis diagnoses in children is rising, being still based on the clinical picture.

Aim
To determine whether triggers of anaphylaxis influence its clinical characteristics in children and adolescents.

Material and methods
The study group included 114 children (5 months–17 years, mean age: 8.0 ±4.8 years), (66%: boys) with the episode of anaphylaxis up to 1 year back. Medical data were entered to the NORA Registry by means of a validated structured on-line questionnaire.

Results
Three most frequent triggers of anaphylaxis were: insect venom (47.4%), food (35.1%), drugs (5.3%), with a predominance of food (egg white, cow’s milk, nuts and peanuts) in the 0–6 years age group, while insect venom (bee predominance) in the 7–17 years age group (p = 0.016). Clinical manifestations differed between food vs. venom allergic reactions and presented as gastro-intestinal (GI) (61.4%) (p = 0.004), respiratory (RS) (93.9%) (p = 0.036), and cardiovascular (CVS) (74.6%) (p = 0.022) symptoms. Among objective symptoms, vomiting was the most common symptom in the 0–2 years age group (47.1%) (p = 0.006), while hypotension in those aged 7 –12 years (40%) (p = 0.010). Severity of symptoms evaluated as Mueller’s grade (IV – 74.5%) and as Ring and Messmer’s grade (III – 65.8%), depended on the trigger (p = 0.028, p = 0.029, respectively). Life-threatening symptoms occurred in 26 children (fall of the blood pressure – 22%, loss of consciousness – 4.4%).

Conclusions
The clinical manifestation of anaphylaxis in children is both trigger and age dependent, irrespective of the gender. A typical patient with food anaphylaxis was younger, presenting predominantly GI symptoms, while a typical patient with venom anaphylaxis was older, with mostly cardiovascular symptoms.

keywords:

Is the clinical manifestation of anaphylaxis in children influenced by the trigger of reaction?

Izabela Tarczoń 1 , Urszula Jedynak-Wąsowicz 2 , Grzegorz Lis 2 , Tomasz Tomasik 2 , Piotr Brzyski 3 , Ewa Cichocka-Jarosz 2

anaphylaxis, children, trigger of anaphylaxis, clinical manifestation

Izabela Tarczoń

¹

,

Urszula Jedynak-Wąsowicz

²

,

Grzegorz Lis

²

,

Tomasz Tomasik

²

,

Piotr Brzyski

³

,

Ewa Cichocka-Jarosz

²