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eISSN: 2084-9893
ISSN: 0033-2526
Dermatology Review/Przegląd Dermatologiczny
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SCImago Journal & Country Rank
5/2020
vol. 107
 
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abstract:
Case report

Isomorphic response in a case of quinolone-induced acute generalized exanthematous pustulosis

Konchok Dorjay
1
,
Soumya Sachdeva
1
,
Surabhi Sinha
1

  1. Dr. Ram Manohar Lohia Hospital and Post Graduate Institute of Medical Education and Research, New Delhi, India
Dermatol Rev/Przegl Dermatol 2020, 107, 454-458
Online publish date: 2020/12/29
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Acute generalized exanthematous pustulosis is a severe, life-threatening, drug-induced cutaneous eruption that is associated with appearance of non-follicular sterile pustules on an erythematous base usually with oedema. We report a case of acute generalized exanthematous pustulosis induced by ofloxacin given for acute diarrhea. The patient was then treated successfully with oral glucocorticosteroids. However, what was notable was that he developed linear non-follicular pustules on the back indicating an isomorphic response (Koebner phenomenon) in acute generalized exanthematous pustulosis, which has not been reported before in the published English literature.
keywords:

acute generalized exanthematous pustulosis, quinolone, isomorphic response, Koebner phenomenon



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