eISSN: 1644-4124
ISSN: 1426-3912
Central European Journal of Immunology
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Review papers
Genetic basis of host innate immune response in mastitis caused by Staphylococcus aureus

Adrianna Pawlik, Grażyna Sender, Rafał Starzyński, Agnieszka Korwin-Kossakowska

(Centr Eur J Immunol 2012; 37 (4): 405-409)
DOI (digital object identifier): 10.5114/ceji.2012.32733
The review briefly describes chosen genes coding for the host innate immunity to staphylococcal infections. There is little known about pathogen – host interactions in such infections. We focus our attention on particular proteins connected with an innate immunity to Staphylococcus aureus during its fundamental steps – pathogen recognition, chemotaxis and immune response regulation process as well as intracellular persistence. Of particular importance is to describe whether mutations, localized in genes, involved in a response to gram-positive bacteria can underlay development of a persistent infection.

bovine mastitis, innate immunity, Staphylococcus aureus

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