eISSN: 2299-0046
ISSN: 1642-395X
Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii
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SCImago Journal & Country Rank
3/2023
vol. 40
 
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abstract:
Review paper

Keratosis follicularis (Darier disease) – clinical characteristics and treatment – a review and update

Katarzyna Chyl-Surdacka
1
,
Adam Borzęcki
1
,
Jakub Latifa
1
,
Monika Turska-Kozłowska
1, 2
,
Marianna Majchrzycka
3

  1. Department of Dermatology, Non-Public Health Care Center ‘Med-Laser’, Lublin, Poland
  2. Department of Molecular Biology, The John Paul II Catholic University of Lublin, Lublin, Poland
  3. Department of Dermatology, Poznan University of Medical Sciences, Poznan, Poland
Adv Dermatol Allergol 2023; XL (3): 337–340
Online publish date: 2023/01/19
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Darier disease is one of the most common genodermatoses. Although Darier disease was described in 1886, targeted therapies remain unknown. Current literature lacks specific guidelines for treatment of Darier disease. Treatment remains symptomatic and may be challenging for dermatologists. The aim of this article is to present clinical characteristics and treatment options. In a mild form of the disease with a small number of skin lesions, the symptoms can be reduced by the use of topical medications. Oral retinoids, alternatively doxycycline, seem to be beneficial in extensive and persistent lesions unresponsive to local treatment. In limited, hypertrophic forms, surgical methods, laser therapy and photodynamic therapy could be used.
keywords:

keratosis follicularis, Darier disease

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