Prognostic factors in systemic sclerosis

Aleksandra Górecka; Elżbieta Szymańska; Irena Walecka

doi:10.5114/dr.2023.134677

eISSN: 2084-9893
ISSN: 0033-2526

Dermatology Review/Przegląd Dermatologiczny

Bieżący numer Archiwum Artykuły zaakceptowane O czasopiśmie Zeszyty specjalne Rada naukowa Bazy indeksacyjne Prenumerata Kontakt Zasady publikacji prac Standardy etyczne i procedury

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Otwarty dostęp

5/2023
vol. 110

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Artykuł przeglądowy

Prognostic factors in systemic sclerosis

Aleksandra Górecka

¹

,

Elżbieta Szymańska

^{1, 2}

,

Irena Walecka

^{1, 2}

Department of Dermatology, National Medical Institute of the Ministry of the Interior and Administration, Warsaw, Poland

Department of Dermatology and Paediatric Dermatology, Centre of Postgraduate Medical Education, Warsaw, Poland

Dermatol Rev/Przegl Dermatol 2023, 110, 608-614

DOI: https://doi.org/10.5114/dr.2023.134677

Data publikacji online: 2024/02/02

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Metryki PlumX:

Systemic sclerosis is a chronic disease involving the connective tissue of the skin and internal organs. It is characterised by disorders of peripheral microcirculation, immune dysregulation, and deposition of collagen fibres and other substances in connective tissue. The most common organ complications in systemic sclerosis include interstitial lung disease, pulmonary arterial hypertension, renal tubular hypertrophy, and arthritis. Imaging findings often precede clinical symptoms, so all patients should be screened as soon as possible, preferably in the asymptomatic phase of the disease. Treatment options for systemic sclerosis include immunomodulatory therapies as well as therapeutic modalities targeting vascular mechanics and connective tissue fibrosis. Efforts are underway to discover new, more sensitive and specific prognostic factors that would help to personalize therapies and thus improve the final treatment outcomes. Identified biomarkers would accelerate the implementation of appropriate treatments, delaying the progression of irreversible complications and decreasing mortality rates in patients.

POLECAMY

KSIĄŻKI

• Atopowe Zapalenie Skóry • Alergologia – kompendium

Indeks osobowy

Prognostic factors in systemic sclerosis

Aleksandra Górecka 1 , Elżbieta Szymańska 1, 2 , Irena Walecka 1, 2

Aleksandra Górecka

¹

,

Elżbieta Szymańska

^{1, 2}

,

Irena Walecka

^{1, 2}