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eISSN: 2084-9893
ISSN: 0033-2526
Dermatology Review/Przegląd Dermatologiczny
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SCImago Journal & Country Rank
3/2018
vol. 105
 
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abstract:
Special paper

Psoriasis. Diagnostic and therapeutic recommendations of the Polish Dermatological Society. Part II: Moderate to severe psoriasis

Adam Reich
,
Jacek Szepietowski
,
Zygmunt Adamski
,
Grażyna Chodorowska
,
Andrzej Kaszuba
,
Dorota Krasowska
,
Aleksandra Lesiak
,
Joanna Maj
,
Joanna Narbutt
,
Agnieszka Osmola-Mańkowska
,
Agnieszka Owczarczyk-Saczonek
,
Witold Owczarek
,
Waldemar Placek
,
Lidia Rudnicka

Dermatol Rev/Przegl Dermatol 2018, 105, 329–357
Online publish date: 2018/07/20
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The second part of diagnostic and therapeutic guidelines of Polish Dermatological Society focuses on moderate and severe psoriasis, in which phototherapy or systemic treatment should be initiated. Currently, it is recommended to treat moderate to severe plaque psoriasis with either classic anti-psoriatic drugs (methotrexate, cyclosporine, acitretin), TNF--inhibitors (adalimumab, etanercept, infliximab), interleukin 12/23 blocking agent (ustekinumab) and new drugs – interleukin-17 inhibitors (secukinumab, ixekizumab) or interleukin 23 inhibitors (guselkumab, tildrakizumab), as well as the new low-molecular weight agents (apremilast, dimethyl fumarate). In some patients, UV-based therapy may be advisable. These recommendations summarize the principles of the use of these agents in patients with psoriasis in dermatological practice. The efficacy and safety of therapy is discussed and available methods to prevent adverse events are summarized.
keywords:

diagnostics, treatment, psoriasis, guidelines, consensus



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