eISSN: 2299-0046
ISSN: 1642-395X
Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii
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SCImago Journal & Country Rank
6/2023
vol. 40
 
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abstract:
Original paper

Selected hormone levels and lipid abnormalities in patients with acne vulgaris

Weronika Szybiak
1
,
Michalina Jarzemska
1
,
Michał Kowalczyk
2
,
Anna Sadowska-Przytocka
3
,
Barbara Więckowska
4
,
Ryszard Żaba
2
,
Katarzyna Lacka
5

  1. Students’ Scientific Society at Poznan University of Medical Sciences, Section of Endocrinology, Poznan University of Medical Sciences, Poznan, Poland
  2. Department of Dermatology and Venereology, Poznan University of Medical Sciences, Poznan, Poland
  3. Department of Dermatology, Poznan University of Medical Sciences, Poznan, Poland
  4. Department of Computer Sciences and Statistics, Poznan University of Medical Sciences, Poznan, Poland
  5. Department of Endocrinology, Metabolism and Internal Medicine, Poznan University of Medical Sciences, Poznan, Poland
Adv Dermatol Allergol 2023; XL (6): 798-807
Online publish date: 2023/12/06
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Introduction:
Acne vulgaris is one of the most common dermatological diseases. Hormonal imbalance affects the skin condition and results in the formation of acne vulgaris lesions.

Aim:
To evaluate serum levels of testosterone, prolactin, luteinizing hormone (LH), follicle-stimulating hormone (FSH), triglycerides (TG), and high-density lipoprotein (HDL) in patients with acne vulgaris and compare them to healthy population.

Material and methods:
Forty-one patients with acne vulgaris and 47 age- and body mass index (BMI)-matched controls were enrolled in the study.

Results:
The mean ± SD testosterone serum level in the study group was 0.45 ±1.03 ng/ml in females and 4.24 ±0.68 in males and in the control group 0.73 ±2.03 ng/ml and 5.3 ±1.3 ng/ml in females and males, respectively. The prolactin serum level was 16.73 ±8.02 ng/ml in the study group and in the control group 13.74 ±8.71 ng/ml (p = 0.011). The FSH serum level was 12.17 ±16.93 mIU/ml and 6.2 ±7.3 mIU/ml in the study and control groups, respectively (p = 0.0001), whereas LH serum levels were 18.44 ±19.71 mIU/ml and 11.26 ±8 mIU/ml, respectively (p = 0.2659). The HDL serum level was 65.63 ±15.67 mg/dl in the study group and 61.53 ±15.89 mg/dl in the control group (p = 0.219), and TG levels were 175.29 ±82.15 mg/dl and 87.32 ±30.64 mg/dl, respectively (p < 0.00001).

Conclusions:
Our study demonstrates, that hormonal and lipid imbalance could be linked to acne vulgaris formation. Evaluation of hormonal and lipid abnormalities could help in treatment decisions and could affect the occurrence of complications and the course of acne.

keywords:

acne vulgaris, hormone profile, lipid profile

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