eISSN: 2299-0038
ISSN: 1643-8876
Menopause Review/Przegląd Menopauzalny
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4/2020
vol. 19
 
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abstract:
Special paper

The outcomes of hypertension treatment depending on gender in patients over 40 years of age

Aleksandra Paduszyńska
1
,
Maciej Banach
1
,
Marek Maciejewski
2
,
Marek Dąbrowa
3
,
Agata Bielecka-Dabrowa
1

  1. Department of Hypertension, Chair of Nephrology and Hypertension, Medical University of Lodz, Lodz, Poland
  2. Department of Cardiology and Congenital Diseases of Adults, Polish Mother's Memorial Hospital Research Institute, Lodz, Poland
  3. Department of Biopharmacy, Chair of Biopharmacy, Medical University of Lodz, Lodz, Poland
Menopause Rev 2020; 19(4): 174-178
Online publish date: 2021/01/07
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Introduction
In women, an increase in blood pressure is observed after the menopause. However, the confounding effect of aging and comorbidities should be taken into account. Current guidelines don’t recommend any specific treatment of post-menopausal hypertension. This study aimed to assess the influence of gender on the outcome of hypertension treatment in patients above 40 years old.

Material and methods
Data for this retrospective, single-center study were collected from the disease cards of hypertensive pharmacologically treated patients hospitalized on the cardiological ward. 268 patients, aged over 40, were divided into two groups: women and men. Additional data regarding compliance and efficacy of treatment after hospitalization were obtained in phone interview. Statistical analysis was performed using the IBM SPSS Statistics25 package.

Results
We analyzed the data in term of comorbidities and medical history of cardiological interventions. The significant differences between studied groups were noted only in the frequency of hyperlipidemia and coronary artery bypass graft, both were more often in men. Significantly more men have been using combined products (24 men – 32.4%) vs. 40 women (20.6%) (p = 0.03). Regarding the drug classes in treatment of hypertension, the only significant difference was observed in the frequency of alfa-blocker use (more often in men). We did not observe any significant difference in the willingness to participate in follow-up between women and men (146, 75.3% vs. 57, 77%, respectively, p = 0.45). There were no significant differences in the follow-up results.

Conclusions
In the studied group of patients, gender did not affect the outcome of hypertension treatment.

keywords:

post-menopausal hypertension, treatment, compliance

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