A case of severe mucosal changes in a patient with
Mycoplasma pneumoniae pneumonia

Marcin Morawski; Magdalena Kaleta; Maria Mroczka; Agnieszka Gawlewicz-Mroczka

doi:10.5114/pja.2025.156078

eISSN: 2391-6052
ISSN: 2353-3854

Alergologia Polska - Polish Journal of Allergology

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4/2025
vol. 12

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abstract:

Case report

A case of severe mucosal changes in a patient with Mycoplasma pneumoniae pneumonia

Marcin Morawski

¹

,

Magdalena Kaleta

²

,

Maria Mroczka

²

,

Agnieszka Gawlewicz-Mroczka

^{1, 2}

Department of Pulmonology and Alergology, University Hospital in Krakow, Poland
Collegium Medicum Jagiellonian University, Krakow, Poland

Alergologia Polska – Polish Journal of Allergology 2025; 12, 4: 315–318

DOI: https://doi.org/10.5114/pja.2025.156078

Online publish date: 2025/11/07

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This case report describes a 45-year-old female, with diagnosis of Mycoplasma pneumoniae pneumonia treated with clarithromycin. The patient developed severe mucosal changes, including crusting of the lips, conjunctivitis and extensive oral erosions, prompting suspicion of Stevens-Johnson syndrome. The patient’s condition was managed with a combination of antibiotics, corticosteroids, and intravenous immunoglobulins, resulting in gradual clinical improvement. This case highlights the challenges in differentiating between drug-induced hypersensitivity and infectious mucocutaneous eruptions, such as reactive infectious mucocutaneous eruption caused by Mycoplasma pneumoniae. Given the rising incidence of Mycoplasma pneumoniae infections, it is essential to consider both infectious and drug-induced causes of severe mucocutaneous reactions.

keywords:

A case of severe mucosal changes in a patient with Mycoplasma pneumoniae pneumonia

Marcin Morawski 1 , Magdalena Kaleta 2 , Maria Mroczka 2 , Agnieszka Gawlewicz-Mroczka 1, 2

pneumonia, Mycoplasma pneumoniae, Stevens-Johnson syndrome, reactive infectious mucocutaneous eruption

Marcin Morawski

¹

,

Magdalena Kaleta

²

,

Maria Mroczka

²

,

Agnieszka Gawlewicz-Mroczka

^{1, 2}