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Alergologia Polska - Polish Journal of Allergology
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1/2024
vol. 11
 
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abstract:
Case report

Allergic response to nasal administration of dexpanthenol in a child. A case report and a review of the literature

Mikołaj Turski
1
,
Małgorzata Łukasiewicz
2
,
Piotr Sajdak
3
,
Seweryn Ziajor
3
,
Artur Bednarski
4
,
Justyna Tomasik
5
,
Marcel Stodolak
1

1.
Department of Pediatrics, E.Szczeklik Specialist Hospital, Tarnów, Poland
2.
CenterMed Medical Centre, Tarnów, Poland
3.
Medical Centre of Łańcut, Poland
4.
Morphological Sciences Department, Institute of Medical Sciences, Medical Collage of University, Rzeszów, Poland
5.
Medical University, Lublin, Poland
Alergologia Polska – Polish Journal of Allergology 2024; 11, 1: 76–79
DOI: https://doi.org/10.5114/pja.2024.135507
Online publish date: 2024/02/17
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A 2-year-old boy with suspected lactose intolerance developed an extensive, itchy rash after using a nasal spray containing dexpanthenol. He was initially treated for a viral upper airway infection with ibuprofen, xylometazoline, and cetirizine. A switch to a drug containing dexpanthenol led to the appearance of the rash and subsequent sleep deprivation. No other possible cause of allergy was found. The withdrawal of all drugs but cetirizine led to full recovery. Dexpanthenol, an alcohol analog of vitamin B5, is present in many drugs for its positive impact on tissue repair. Although generally considered safe, it may rarely cause an allergic reaction, hence we underscore the importance of considering dexpanthenol oversensitivity in patients with unexplained widespread rashes, particularly in pediatric cases.
keywords:

rash, dexpanthenol allergy, allergic reaction, dexpanthenol oversensitivity, widespread rash



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