Polish Journal of Thoracic and Cardiovascular Surgery
eISSN: 1897-4252
ISSN: 1731-5530
Kardiochirurgia i Torakochirurgia Polska/Polish Journal of Thoracic and Cardiovascular Surgery
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3/2025
vol. 22
 
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abstract:
Review paper

Artificial intelligence nanoparticle-based drug delivery systems and targeted delivery of therapeutics for the treatment of cardiovascular diseases: a systematic review

Fatemeh Kamali
1
,
Seyedehmahrokh Moosavimordghafari
1
,
Mohammad Ghasemian
1
,
Narges Kamali
1
,
Seyedeh Mahta Mojab
2
,
Fatemeh Nikfard
1
,
Zahra Nikfard
1
,
Saber Bakhtiaryfar
3

  1. Pharmacy student, School of Pharmacy, Zhengzhou University, Zhengzhou, Henan, China
  2. Medical student, School of Medicine, Jilin University, Jilin, China
  3. Medical student, School of Medicine, Zhengzhou University, Zhengzhou, Henan, China
Kardiochirurgia i Torakochirurgia Polska 2025; 22 (3): 182-189
DOI: https://doi.org/10.5114/kitp.2025.154852
Online publish date: 2025/10/29
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This article reviews the progress of nanoparticles as drug carriers in the treatment of cardiovascular diseases, and how nanoparticles can deliver anti-inflammatory, anti-proliferative, and anticoagulant drugs directly to the surgical site in surgical procedures. For this, 45 articles published between 2005 and 2024 with keywords including “Artificial intelligence Nanoparticle”, “Emergency Medicine Unit”, and “Therapeutic for the treatment of cardiovascular diseases” in Scopus, Elsevier, Web of Science and ScienceDirect were reviewed. Nanoparticle-based drug delivery systems have demonstrated several noteworthy therapeutic benefits in the treatment of cardiovascular disorders since they were first used in the cancer field to deliver safer and more effective chemotherapeutics. By delivering targeted and site-specific medications with controlled release, nanoparticle-based drug delivery systems modify the biodistribution of therapeutic agents. An optimal material for cardiovascular therapeutics would be a nanoparticle based on metal, lipid, or polymer.
keywords:

artificial intelligence, nanoparticle, drug delivery systems, therapeutic
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