Przegląd Gastroenterologiczny
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1/2026
vol. 21
 
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Artykuł oryginalny

Dynamic platelet count value as a clinical indicator of postoperative pancreatic fistula after pancreatic resections

Maria Papadoliopoulou
1
,
Francesk Mulita
2
,
Ioannis Margaris
1
,
Mirto Moutafi
3
,
Dimitrios Vouros
4
,
Theodoros Sidiropoulos
1
,
Panagiotis Kokoropoulos
1
,
Konstantinos Toutouzas
4
,
Nikolaos V. Michalopoulos
4
,
Nikolaos Arkadopoulos
1

  1. 4th Department of Surgery, Attikon University Hospital, School of Medicine, National and Kapodistrian University of Athens, Greece
  2. Department of Surgery, General University Hospital of Patras, Greece
  3. Section of Medical Oncology, 2nd Department of Internal Medicine, Attikon University Hospital, School of Medicine, National and Kapodistrian University of Athens, Greece
  4. 1st Propaedeutic Department of Surgery, Hippocration General Hospital, School of Medicine, National and Kapodistrian University of Athens, Greece
Gastroenterology Rev 2026; 21 (1): 97–102
DOI: https://doi.org/10.5114/pg.2026.160542
Data publikacji online: 2026/03/27
Plik artykułu:
- Dynamic platelet.pdf  [0.10 MB]
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Metryki PlumX:
 
1. Hackert T, Werner J, Büchler MW. Postoperative pancreatic fistula. Surgeon 2011; 9: 211-7.
2. Hackert T, Hinz U, Pausch T, et al. Postoperative pancreatic fistula: we need to redefine grades B and C. Surgery 2016; 159: 872-7.
3. Hackert T, Werner J, Büchler MW. Postoperative pancreatic fistula. Surgeon 2011; 9: 211-7.
4. Smits FJ, Molenaar IQ, Besselink MG, et al. Early recognition of clinically relevant postoperative pancreatic fistula: a systematic review. HPB (Oxford) 2020; 22: 1-11.
5. 5. Ma T, Bai X, Chen W, et al. Surgical management and outcome of grade-C pancreatic fistulas after pancreaticoduodenectomy: a retrospective multicenter cohort study. Int J Surg 2019; 68: 27-34.
6. Bassi C, Marchegiani G, Dervenis C, et al. The 2016 update of the International Study Group (ISGPS) definition and grading of postoperative pancreatic fistula: 11 years after. Surgery 2017; 161: 584-91. Erratum: Surgery 2024; 176: 988-9.
7. Özşay O, Aydin MC, Çelik SC, et al. Serum amylase on postoperative day one is a strong predictor of pancreatic fistula after pancreaticoduodenectomy: a retrospective cohort. Turk J Med Sci 2023; 53: 1271-80.
8. Chui JN, Ziaziaris WA, Nahm CB, et al. Lipase-to-amylase ratio for the prediction of clinically relevant postoperative pancreatic fistula following pancreaticoduodenectomy. Pancreas 2024; 53: e579-87.
9. Büyükkasap AÇ, Dikmen K, Yavuz A, et al. Predictive value of drain fluid amylase level on postoperative day one after pancreatic resection for predicting postoperative pancreatic fistula. Turk J Surg 2024; 40: 19-27.
10. Lale A, Kirmizi I, Hark BD, et al. Predictors of postoperative pancreatic fistula (POPF) after pancreaticoduodenectomy: clinical significance of the mean platelet volume (MPV)/platelet count ratio as a new predictor. J Gastrointest Surg 2022; 26: 387-97.
11. Nicolai L, Massberg S. Platelets as key players in inflammation and infection. Curr Opin Hematol 2020; 27: 34-40.
12. Jenne CN, Kubes P. Platelets in inflammation and infection. Platelets 2015; 26: 286-92.
13. Franco AT, Corken A, Ware J. Platelets at the interface of thrombosis, inflammation, and cancer. Blood 2015; 126: 582-8.
14. Klinger MH. Platelets and inflammation. Anat Embryol (Berl) 1997; 196: 1-11.
15. Thomas MR, Storey RF. The role of platelets in inflammation. Thromb Haemost 2015; 114: 449-58.
16. von Hundelshausen P, Weber C. Platelets as immune cells: bridging inflammation and cardiovascular disease. Circ Res 2007; 100: 27-40.
17. Greco E, Lupia E, Bosco O, et al. Platelets and multi-organ failure in sepsis. Int J Mol Sci 2017; 18: 2200.
18. Del Conde I, Crúz MA, Zhang H, et al. Platelet activation leads to activation and propagation of the complement system. J Exp Med 2005; 201: 871-9.
19. Clark SR, Ma AC, Tavener SA, et al. Platelet TLR4 activates neutrophil extracellular traps to ensnare bacteria in septic blood. Nat Med 2007; 13: 463-9.
20. Chang JH, Stackhouse K, Dahdaleh F, et al. Postoperative day 1 drain amylase after pancreatoduodenectomy: optimal level to predict pancreatic fistula. J Gastrointest Surg 2023; 27: 2676-83.
21. Clements NA, Philips P, Egger ME, et al. Combined pre-operative risk score predicts pancreatic leak after pancreatic resection. Surg Endosc 2024; 38: 742-56.
22. Izumo W, Higuchi R, Yazawa T, et al. Evaluation of preoperative risk factors for postpancreatectomy hemorrhage. Langenbecks Arch Surg 2019; 404: 967-74.
23. van Dongen JC, van Dam JL, Besselink MG, et al. Fistula risk score for auditing pancreatoduodenectomy: the auditing-FRS. Ann Surg 2023; 278: e272-7.
24. Turner KM, Delman AM, Lim SA, et al. Contemporary outcomes of grade-c postoperative pancreatic fistula in a nationwide database. J Surg Res 2024; 296: 302-9.
25. Ma M, Li G, Zhou B, et al. Comprehensive analysis of the association between inflammation indexes and complications in patients undergoing pancreaticoduodenectomy. Front Immunol 2023; 14: 1303283.
26. Kinaci E, Sevinc MM, Ozakay A, et al. Intraoperative acidosis is a new predictor for postoperative pancreatic fistula after pancreaticoduodenectomy. Hepatobiliary Pancreat Dis Int 2016; 15: 302-9.
27. El Asmar A, Ghabi E, Akl B, et al. Preoperative NLR and PLR are predictive of clinically relevant postoperative pancreatic fistula. Surg Pract Sci 2022; 10: 100122.
28. Kanda M, Fujii T, Takami H, et al. Novel diagnostics for aggravating pancreatic fistulas at the acute phase after pancreatectomy. World J Gastroenterol 2014; 20: 8535-44.
29. Heard JC, Smith GH, Tolman A, et al. No drain, no problem: serum-based marker prediction of clinically relevant postoperative pancreatic fistula. Am Surg 2024; 90: 1074-81.
30. Lopez P, Pando E, Ortega-Torrecilla N, et al. The role of clinically relevant intra-abdominal collections after pancreaticoduodenectomy: clinical impact and predictors. A retrospective analysis from a European tertiary centre. Langenbecks Arch Surg 2023; 409: 21.
31. Wang Q, Wang Z, Liu F, et al. Machine learning-based prediction of postoperative pancreatic fistula after laparoscopic pancreaticoduodenectomy. BMC Surg 2025; 25: 191.
Copyright: © 2026 Termedia Sp. z o. o. This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) License (http://creativecommons.org/licenses/by-nc-sa/4.0/), allowing third parties to copy and redistribute the material in any medium or format and to remix, transform, and build upon the material, provided the original work is properly cited and states its license.



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