Abstract
4/2025
vol. 19
Review paper
Effect of analgesia plus placebo on low back pain – a systematic review and meta-analysis
- Department of Orthopedic Surgery, Urmia University of Medical Sciences, Urmia, Iran
- Department of Anesthesiology, Urmia University of Medical Sciences, Urmia, Iran
- Resident of the Cardiology, Tabriz University of Medical Sciences, Tabriz, Iran
- General Practitioner, Urmia University of Medical Sciences, Urmia, Iran
Pielęgniarstwo Chirurgiczne i Angiologiczne 2025; 19(4): 135–140
Online publish date: 2025/11/05
In the present study, the effect of analgesia plus placebo on low back pain was investigated. The researchers of the current study searched for key words associated with its goals in the international databases Scopus, Cochrane, Embase, and MEDLINE (PubMed) for January 2014 – December 2024 using 95% CI effect size using inverse-variance techniques and a fixed-effects model. Stata was used for the meta-analysis (version 17). The meta-analysis showed that use of medication plus placebo can reduce low back pain by 84% [ES 0.84 (–0.25, 1.92), I2 = 0%]. In conclusion, when compared to medication plus placebo, adding Diclofenac, Tramadol, Tizanidine, Aceclofenac, Thiocolchicoside, Naproxen, Metaxalone, Baclofen, and Ibuprofen does not improve functioning or pain for acute low back pain.
Keywords
back pain, local anesthesia, nerve, spine
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