Esophageal diverticula occur with a frequency of 2/100,000/year. The most common location of acquired single diverticula is the cervical part of the esophagus, which mainly concerns patients in the 7th decade of life [1]. Multiple diverticula of the middle part of the esophagus are a rare condition and occur with a frequency of 1/500,000/year [2].
A 49-old-year woman was admitted to the hospital due to solid food dysphagia associated with retrosternal pain, malnutrition and loss of 8 kg of weight during the last year. Her weight was 47 kg and body mass index (BMI) 19.56 kg/m² at the time of admittance. The symptoms of the disease had been developing gradually for a few years. Diverticulosis of the thoracic part of the esophagus had been confirmed endoscopically 3 years ago before hospitalization. She had received steroids for a long time due to systemic lupus erythematosus (SLE). The steroid treatment was complicated with side effects such as osteoporosis and loss of menstruation at the age of 39 years. Attempts of abundant drinking did not improve swallowing in spite of lack of structural stenosis confirmed in endoscopy examination. It was decided to perform subtotal minimally invasive esophagectomy (laparoscopy with right videothoracoscopy-VATS and cervicotomy) (Figs. 1, 2). The VATS procedure was performed in the prone position. The postoperative period was uneventful with full restoration of swallowing. A histopathologic specimen of the resected esophagus confirmed chronic inflammatory changes in the multiple diverticula walls of the resected esophagus.
Single diverticula of the cervical and epiphrenic part of the esophagus arise by a “pushing mechanism” whereas diverticula at the level of the tracheal bifurcation arise by a “pulling mechanism” [3, 4]. Disorders of esophageal motility, diffuse esophageal spasm and achalasia are the base of arising multiple diverticula or diverticulosis in the thoracic part of the esophagus [5, 6]. There is no relationship between SLE and esophageal motility disorders and diverticulosis reported in the literature; however, it would have been strongly associated in the present case. This theory would be confirmed by absence of stenosis in the endoscopic examination. Exacerbation of clinical symptoms as dysphagia, pain, malnutrition, and food retention depends on the shape and size of the diverticula. The seven diverticula were confirmed in the case, but five of them with a multicentimeter size...


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