eISSN: 1897-4252
ISSN: 1731-5530
Kardiochirurgia i Torakochirurgia Polska/Polish Journal of Thoracic and Cardiovascular Surgery
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3/2021
vol. 18
 
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abstract:
Original paper

Factors influencing the effect of surgical treatment in secondary proliferative disease with lung involvement

Jarosław Religioni
1
,
Daniel Rabczenko
2
,
Tadeusz Orłowski
1

1.
Institute of Tuberculosis and Lung Diseases, Warsaw, Poland
2.
Department of Monitoring and Analysis of Population Health Status, National Institute of Public Health – National Institute of Hygiene, Warsaw, Poland
Kardiochirurgia i Torakochirurgia Polska 2021; 18 (3): 131-138
Online publish date: 2021/10/05
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Introduction
Surgical treatment of neoplastic lung metastases is a big therapeutic problem, at the stage of qualifying for the procedure, in the surgical technique itself, and in the tactics of managing subsequent disease relapses. The most doubtful aspect is determining which factors influence the prolongation of survival in patients with such a diagnosis.
Aim: To determine which factors influence the effectiveness of surgical treatment of neoplastic metastases to the lungs.

Material and methods
A group of 577 patients was subjected to the study. An analysis of all performed operations (1009) was also carried out according to the set goals. Statistical analysis was performed using the estimates of the c2 test, Kaplan-Meier estimator, and log-rank test.

Results
It was established what statistically significant factors may improve the treatment effectiveness. It was found that the lack of radicalism was influenced by: the number of lung metastases, the presence of changes in the lymph nodes, age, histology of the primary tumor and its location, and the number of treatments. Nodal metastases are more common in non-radical procedures, depend on the patient’s age, are more often found in unilateral procedures, and depend on the location and histology of the primary tumor.

Conclusions
It was found that the radical nature of the procedure did not affect the progression of the disease, but it did have an impact on survival. Relapses are more common in bilateral procedures, reducing survival. Lymph node metastases worsen the prognosis.

keywords:

lung metastases, radical treatment, recurrence after resection, lymph node metastases

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