eISSN: 1897-4252
ISSN: 1731-5530
Kardiochirurgia i Torakochirurgia Polska/Polish Journal of Thoracic and Cardiovascular Surgery
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1/2012
vol. 9
 
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abstract:

NIEWYDOLNOŚĆ SERCA I PŁUC, TRANSPLANTOLOGIA
Successful use of cidofovir to treat refractory cytomegalovirus infection in heart transplant recipient – a case report

Anna Krynicka-Mazurek
,
Michał Zakliczyński
,
Jerzy Nożyński
,
Roman Przybylski
,
Marian Zembala

Kardiochirurgia i Torakochirurgia Polska 2012; 1: 78–81
Online publish date: 2012/03/31
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Cytomegalovirus (CMV) infection poses a serious risk to patients after organ transplantation. It affects not only the early postoperative period, but through indirect effects contributes to shortening the long-term survival. CMV infection typically occurs within the period from the 2nd to the 6th month after organ transplantation. CMV infection that presents after 6 months is described as late CMV disease. Late onset CMV infection may present in an atypical way; therefore the diagnosis of CMV disease should be taken into consideration at any time after transplantation. In this article we present a clinical case of atypical CMV infection in a patient after orthotopic heart transplantation. It was unusual because of the timing and because of the lack of characteristic signs and symptoms. We also describe our experiences with cidofovir, a second-line antiviral drug, which is rarely used in patients after solid organ transplantation.
keywords:

CMV infection, orthotopic heart transplantation, cidofovir
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