eISSN: 2299-0038
ISSN: 1643-8876
Menopause Review/Przegląd Menopauzalny
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SCImago Journal & Country Rank
 
3/2020
vol. 19
 
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abstract:
Original paper

Nipple-sparing mastectomy with immediate breast reconstruction – early complications and outcomes of the treatment

Artur Bocian
1
,
Piotr Kędzierawski
2, 3
,
Krzysztof Kurczych
1
,
Przemysław Jasnowski
4
,
Daniel Maliszewski
5
,
Agnieszka Kołacińska
6

1.
Department of Surgical Oncology, Holycross Cancer Centre, Kielce, Poland
2.
Institute of the Health Sciences, Collegium Medicum, Jan Kochanowski University, Kielce, Poland
3.
Department of Radiotherapy, Holycross Cancer Centre, Kielce, Poland
4.
Department of Surgical Oncology with Sub-unit for the Treatment of Breast Diseases, The Holy Virgin Mary Provincial Specialist Hospital, Częstochowa, Poland
5.
Department of Surgical Oncology, Janusz Korczak Provincial Specialist Hospital, Słupsk, Poland
6.
Department of Head and Neck Cancer Surgery, Breast Cancer Unit, Medical University of Łódź, Poland
Menopause Rev 2020; 19(3): 117-122
Online publish date: 2020/10/02
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Introduction
To assess the early complications and outcomes of the treatment of patients undergoing nipple-sparing mastectomy (NSM) with immediate breast reconstruction.

Material and methods
A retrospective study was performed on 120 patients who underwent 130 NSM (10 bilateral) procedures between 1.01.2015 and 31.12.2017 in two oncology centers in Poland. In 80 patients a breast cancer was recognized. Sixteen patients underwent operations on the basis of being carriers of the BRCA1 mutation. The follow-up period ranged from 10 to 34 months. The NSM procedures were performed with or without skin reduction and a free nipple-areola complex (NAC) transplant, with 130 prosthetic devices inserted subpectorally. Breast cancer patients followed the standard protocol for adjuvant therapy.

Results
The patients for risk-reducing mastectomies were younger. Prevalent histology was no special type (NST) in 60 out of 80 patients, mean tumor – NAC distance was 43.3 mm. The prevalent biological subtype was Luminal B HER2-negative. Adjuvant management consisted of chemotherapy in 61 and radiotherapy in 35 patients. We noted 14 cases of complications, 13 in the cancer group, and 1 in the non-cancer group. Skin necrosis was the most common. The mean time for the appearance of the complications was 2.8 months. No local recurrences were observed

Conclusions
NSM is a safe and effective surgical option for qualified patients with breast cancer and in risk-reducing mastectomies.

keywords:

breast cancer, BRCA1, subcutaneous mastectomy, immediate breast reconstruction

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