Propofol is an intravenously administered, short-acting general anesthetic. It has sedative-hypnotic and antiepileptic properties, but it is devoid of analgesic activity. Long-term use of this drug has a potential for addiction. The scientific literature increasingly reports the problem of recreational abuse of propofol (it causes mild euphoria, hallucinations, and sexual disinhibition, among other things), primarily by anesthesiologists. This is, of course, due to the easy access to anesthetics in this professional group. The high psychological burden associated with working in difficult conditions (emergency conditions, direct threat to patient life) translates into a higher rate of suicide and addiction, including drug addiction, than in other specialties. This problem is particularly significant because drugs used in anesthesiology and intensive care are characterized by a high mortality rate in cases of accidental or intentional overdose. Therefore, it seems advisable to increase control over access to this drug and to inform medical and nursing communities about the signs of addiction among members of these professions.