Assessment of IL-6 activity in cervico-vaginal mucus connected 
with cervical length concerning elderly pregnant women over 35 years 
of age at a risk of preterm delivery

Paweł Pawłowicz; Wojciech Rawski; Katarzyna Grzebyk; Tomasz Stetkiewicz; Grzegorz Jakiel

Abstract

1/2011 vol. 10

Original paper

Assessment of IL-6 activity in cervico-vaginal mucus connected with cervical length concerning elderly pregnant women over 35 years of age at a risk of preterm delivery

Paweł Pawłowicz

,

Wojciech Rawski

,

Katarzyna Grzebyk

,

Tomasz Stetkiewicz

,

Grzegorz Jakiel

Przegląd Menopauzalny 2011; 1: 37–39

Online publish date: 2011/03/16

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AMA

Pawłowicz P, Rawski W, Grzebyk K, Stetkiewicz T, Jakiel G. Assessment of IL-6 activity in cervico-vaginal mucus connected with cervical length concerning elderly pregnant women over 35 years of age at a risk of preterm delivery. Menopause Review/Przegląd Menopauzalny. 2011;10(1):37-39.

APA

Pawłowicz, P., Rawski, W., Grzebyk, K., Stetkiewicz, T., & Jakiel, G. (2011). Assessment of IL-6 activity in cervico-vaginal mucus connected with cervical length concerning elderly pregnant women over 35 years of age at a risk of preterm delivery. Menopause Review/Przegląd Menopauzalny, 10(1), 37-39.

Chicago

Pawłowicz, Paweł, Wojciech Rawski, Katarzyna Grzebyk, Tomasz Stetkiewicz, and Grzegorz Jakiel. 2011. "Assessment of IL-6 activity in cervico-vaginal mucus connected with cervical length concerning elderly pregnant women over 35 years of age at a risk of preterm delivery". Menopause Review/Przegląd Menopauzalny 10 (1): 37-39.

Harvard

Pawłowicz, P., Rawski, W., Grzebyk, K., Stetkiewicz, T., and Jakiel, G. (2011). Assessment of IL-6 activity in cervico-vaginal mucus connected with cervical length concerning elderly pregnant women over 35 years of age at a risk of preterm delivery. Menopause Review/Przegląd Menopauzalny, 10(1), pp.37-39.

MLA

Pawłowicz, Paweł et al. "Assessment of IL-6 activity in cervico-vaginal mucus connected with cervical length concerning elderly pregnant women over 35 years of age at a risk of preterm delivery." Menopause Review/Przegląd Menopauzalny, vol. 10, no. 1, 2011, pp. 37-39.

Vancouver

Pawłowicz P, Rawski W, Grzebyk K, Stetkiewicz T, Jakiel G. Assessment of IL-6 activity in cervico-vaginal mucus connected with cervical length concerning elderly pregnant women over 35 years of age at a risk of preterm delivery. Menopause Review/Przegląd Menopauzalny. 2011;10(1):37-39.

Inerleukin-6 is a pleiotropic cytokine with multidirectional influence on the cells of both innate and adaptive immune system. The main role of IL-6 is to initiate and regulate acute inflammatory response and adaptive immunity. It has a number of physiological effects. Overproduction of IL-6 causes a change from acute to chronic inflammation. Its higher concentration may initiate premature occurrence of preterm uterine contractions. Preterm delivery is the main reason for perinatal mortality and morbidity of neonates. Pro-inflammatory cytokines, mainly IL-1 and IL-6, which stimulate prostaglandin production are considered to be crucial reasons for preterm delivery.