To increase body height and muscle strength – one medicine for two diseases? Case report of a boy with Silver-Russell syndrome and Duchenne muscular dystrophy
Joanna A. Chrzanowska
1
,
Lidia Bubula
2
,
Anna Noczyńska
1
,
Agnieszka Zubkiewicz-Kucharska
1
Department of Endocrinology and Diabetology of the Developmental Age, Medical University of Wroclaw, Poland
Student Scientific Club at the Department of Endocrinology and Diabetology of the Developmental Age, Medical University of Wroclaw, Poland
A. Chrzanowska J, Bubula L, Noczyńska A, Zubkiewicz-Kucharska A. To increase body height and muscle strength – one medicine for two diseases? Case report of a boy with Silver-Russell syndrome and Duchenne muscular dystrophy. Pediatric Endocrinology Diabetes and Metabolism. 2021;27(4):298-304. doi:10.5114/pedm.2021.107724.
APA
A. Chrzanowska, J., Bubula, L., Noczyńska, A., & Zubkiewicz-Kucharska, A. (2021). To increase body height and muscle strength – one medicine for two diseases? Case report of a boy with Silver-Russell syndrome and Duchenne muscular dystrophy. Pediatric Endocrinology Diabetes and Metabolism, 27(4), 298-304. https://doi.org/10.5114/pedm.2021.107724
Chicago
A. Chrzanowska, Joanna, Lidia Bubula, Anna Noczyńska, and Agnieszka Zubkiewicz-Kucharska. 2021. "To increase body height and muscle strength – one medicine for two diseases? Case report of a boy with Silver-Russell syndrome and Duchenne muscular dystrophy". Pediatric Endocrinology Diabetes and Metabolism 27 (4): 298-304. doi:10.5114/pedm.2021.107724.
Harvard
A. Chrzanowska, J., Bubula, L., Noczyńska, A., and Zubkiewicz-Kucharska, A. (2021). To increase body height and muscle strength – one medicine for two diseases? Case report of a boy with Silver-Russell syndrome and Duchenne muscular dystrophy. Pediatric Endocrinology Diabetes and Metabolism, 27(4), pp.298-304. https://doi.org/10.5114/pedm.2021.107724
MLA
A. Chrzanowska, Joanna et al. "To increase body height and muscle strength – one medicine for two diseases? Case report of a boy with Silver-Russell syndrome and Duchenne muscular dystrophy." Pediatric Endocrinology Diabetes and Metabolism, vol. 27, no. 4, 2021, pp. 298-304. doi:10.5114/pedm.2021.107724.
Vancouver
A. Chrzanowska J, Bubula L, Noczyńska A, Zubkiewicz-Kucharska A. To increase body height and muscle strength – one medicine for two diseases? Case report of a boy with Silver-Russell syndrome and Duchenne muscular dystrophy. Pediatric Endocrinology Diabetes and Metabolism. 2021;27(4):298-304. doi:10.5114/pedm.2021.107724.
The coexistence of 2 genetic diseases can mutually modify their course. We describe the case of a 10-year-old boy with Sliver-Russell syndrome (SRS) and Duchenne muscular dystrophy (DMD). The patient's short stature, which is part of the clinical picture of both diseases, has been additionally aggravated by the steroid therapy, which is necessary to delay the progression of DMD. From the age of 9 years, the patient was treated with recombinant human growth hormone (rhGH) for 18 months. The following study discusses whether rhGH therapy in a child with SRS and DMD may alleviate or worsen the course of DMD, and how it affects carbohydrate metabolism disorders.
