eISSN: 2081-2841
ISSN: 1689-832X
Journal of Contemporary Brachytherapy
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5/2020
vol. 12
 
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abstract:
Case report

Salvage high-dose-rate interstitial brachytherapy for perineal recurrence of prostate cancer after surgery and radiotherapy: a case report

Andrea Vavassori
1
,
Stefano Durante
1
,
Matteo Augugliaro
1
,
Stefania Comi
2
,
Raffaella Cambria
2
,
Federica Cattani
2
,
Roberta Lazzari
1
,
Deliu Victor Matei
3
,
Ottavio De Cobelli
3, 4
,
Roberto Orecchia
5
,
Barbara Alicja Jereczek-Fossa
1, 4

1.
Department of Radiotherapy, IEO European Institute of Oncology IRCCS, Milan, Italy
2.
Unit of Medical Physics, IEO European Institute of Oncology IRCCS, Milan, Italy
3.
Department of Urology, IEO European Institute of Oncology IRCCS, Milan, Italy
4.
Department of Oncology and Hemato-Oncology, University of Milan, Milan, Italy
5.
Scientific Directorate, IEO European Institute of Oncology IRCCS, Milan, Italy
J Contemp Brachytherapy 2020; 12, 5: 492–496
DOI: https://doi.org/10.5114/jcb.2020.100383
Online publish date: 2020/10/30
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Perineal seeding of tumor cells from prostate cancer (PCa) is very rare, and no standard treatment exists for this atypical presentation with no evidence of distant metastases. Local excision or external beam radiotherapy are used as local salvage treatments for such perineal masses, including those occurring after biopsy, surgery, or interstitial brachytherapy.

We report on a patient who presented no evidence of disease and no late urinary or gastrointestinal toxicities at 58 months after receiving high-dose-rate brachytherapy (HDR-BT) for perineal recurrence of PCa after radical prostatectomy and salvage external beam radiotherapy. To the best of our knowledge, this is the first case treated with HDR-BT in this scenario.
keywords:

interstitial HDR brachytherapy, perineal prostate cancer recurrence, reirradiation

  
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