Abstract
1/2013
vol. 12
Review paper
New clinical data and guidelines on menopausal hormone therapy since the Women’s Health Initiative study: route of administration and safety profile
Przegląd Menopauzalny 2013; 1: 83–86
Online publish date: 2013/03/05
New data and guidelines on menopausal hormone therapy have become available since the publication of
the Women’s Health Initiative study. This article is aimed to update information regarding the mmendations
for the administration route and benefit-risk profile of menopausal hormone therapy. The clinical guidelines
generally do not recommend any particular route as better than the others. Available data show that use
of transdermal estradiol and micronized progesterone may reduce the risk of venous thromboembolism, breast cancer, stroke, and coronary heart disease.
the Women’s Health Initiative study. This article is aimed to update information regarding the mmendations
for the administration route and benefit-risk profile of menopausal hormone therapy. The clinical guidelines
generally do not recommend any particular route as better than the others. Available data show that use
of transdermal estradiol and micronized progesterone may reduce the risk of venous thromboembolism, breast cancer, stroke, and coronary heart disease.
Keywords
menopausal hormone therapy, transdermal therapy, venous thromboembolism, breast cancer, stroke, coronary heart disease
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