eISSN: 1897-4252
ISSN: 1731-5530
Kardiochirurgia i Torakochirurgia Polska/Polish Journal of Thoracic and Cardiovascular Surgery
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1/2011
vol. 8
 
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abstract:

Surgical treatment of congenital heart malformation with left-to-right shunt coexists with pulmonary hypertension

Krzysztof Mozol
,
Ewelina Kwaśniak
,
Ireneusz Haponiuk
,
Adam Szafranek
,
Bohdan Maruszewski

Kardiochirurgia i Torakochirurgia Polska 2011; 8 (1): 66–70
Online publish date: 2011/04/13
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Pulmonary hypertension is a significant risk factor of mortality and morbidity in congenital heart malformations with left-to-right shunt. The increased pulmonary blood flow lead to permanent endothelial cells stimulation, consequently to their dysfunction, increased pulmonary vascular resistance, acute or progressive right ventricle failure. The early surgical correction prevent up mention pathological tract. The optimal time of surgery is still leading therapeutic problem. The specific and non-specific treatment of pulmonary vascular resistance would improve surgical results. Extracorporeal membrane oxygenation (ECMO) or lung or heart – lung transplantation are option for patients with contraindications for surgical treatment and/or resistance for up mention treatment.
keywords:

pulmonary hypertension, congenital heart malformations, increased pulmonary blood flow
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