eISSN: 2081-2841
ISSN: 1689-832X
Journal of Contemporary Brachytherapy
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3/2023
vol. 15
 
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abstract:
Original paper

Multilayer intensity modulated contact interventional radiotherapy (brachytherapy): Stretching the therapeutic window in skin cancer

Bruno Fionda
1
,
Elisa Placidi
2
,
Enrico Rosa
3
,
Valentina Lancellotta
1
,
Gerardina Stimato
2
,
Martina De Angeli
1
,
Francesco Giuseppe Ciardo
4
,
Patrizia Cornacchione
1
,
Frank-Andre Siebert
5
,
Luca Tagliaferri
1
,
Luca Indovina
2

  1. U.O.C. Radioterapia Oncologica, Dipartimento di Diagnostica per Immagini, Radioterapia Oncologica Ed Ematologia, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy
  2. U.O.S.D. Fisica Medica e Radioprotezione, Dipartimento di Diagnostica per Immagini, Radioterapia Oncologica ed Ematologia, Fondazione Policlinico Universitario Agostino Gemelli, IRCCS, Rome, Italy
  3. Istituto di Fisica, Università Cattolica del Sacro Cuore, Rome, Italy
  4. Istituto di Radiologia, Università Cattolica del Sacro Cuore, Rome, Italy
  5. Clinic of Radiotherapy, University Hospital of Schleswig-Holstein, Campus Kiel, Germany
J Contemp Brachytherapy 2023; 15, 3: 220–223
DOI: https://doi.org/10.5114/jcb.2023.127837
Online publish date: 2023/06/01
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Interventional radiotherapy (IRT, brachytherapy) is a highly effective treatment method for non-melanoma skin cancer (NMSC). Traditionally, the maximum depth of NMSC lesions considered eligible for contact IRT was 5 mm; however, following several national surveys and recent recommendations, such cut-off, lesions thicker than 5 mm may be treated by contact IRT. The use of image guidance in defining the actual depth in treating NMSC to correctly identify clinical target volume (CTV) and prevent unnecessary toxicity is of paramount importance.

The aim of the paper was to describe a multilayer arrangement of catheters to treat NMSC lesions thicker than 5 mm, thus proposing an example of dynamic intensity modulated IRT, using different catheter-to-skin distance of sources to reach the best CTV coverage and maximally reduce the excess of dose to the skin.
keywords:

interventional radiotherapy, brachytherapy, skin cancer, intensity modulated, therapeutic window

  
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