eISSN: 2081-2841
ISSN: 1689-832X
Journal of Contemporary Brachytherapy
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4/2014
vol. 6
 
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abstract:

Original paper
The use of an interstitial boost in the conservative treatment of breast cancer: how to perform it routinely in a radiotherapy department

Cristina Gutiérrez
,
Dina Najjari
,
Evelyn Martínez
,
Saray Botella
,
Arantxa Eraso
,
Francisco Pino
,
Ferran Moreno
,
Joan Pera
,
Ferran Guedea

J Contemp Brachytherapy 2014; 6, 4: 397–403
Online publish date: 2014/11/17
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Purpose: To demonstrate the utility of a boost with interstitial brachytherapy (BT) in breast-conserving therapy (BCT) by doing a thorough review of the literature and describing in detail our technique for delivering this boost.

Material and methods: Our department has been delivering the boost with interstitial BT since 1989, in most cases with rigid needles and a theoretical dosimetry. In the early years, we used low-dose-rate (LDR) with iridium-192 wires. The dose administered was 15 Gy if there were no risk factors for local relapse or 20-25 Gy in the presence of risk factors. The risk factors considered were the presence of a close margin (less than 10 mm) and an extensive intraductal component (more than 25%). After 2002, we switched to high-dose-rate (HDR); using the linear quadratic model we changed the low dose to 3 fractions of 4.5 Gy in the case of no risk factors for local relapse or to 3 fractions of 5 Gy in the presence of risk factors.

Results: In 79 consecutive boost patients treated in our department between 2010 and 2011, with a median follow-up of 46 months, the local control rate was 97.47%. With respect to cosmesis, fibrosis occurred in 17 cases (21.5%) and hyperpigmentation in 26 cases (32.9%). Our hospital’s results are comparable in terms of local control and cosmesis to those of other authors.

Conclusions: This educational article describes our department’s boost technique with rigid needles and comments briefly on our results using this technique in a group of consecutively treated patients in our department. A review of the literature and the published results on local control and cosmesis is also described.
keywords:

brachytherapy, breast cancer, breast conserving therapy, interstitial boost

 
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