Subglottis stenosis in Wegener’s granulomatosis

Elżbieta Wiatr

eISSN: 2084-9842
ISSN: 1643-9279

Postępy w chirurgii głowy i szyi/Advances in Head and Neck Surgery

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2/2009
vol. 8

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abstract:

Subglottis stenosis in Wegener’s granulomatosis

Elżbieta Wiatr

Postępy w chirurgii głowy i szyi 2009; 2: 19–22

Online publish date: 2009/10/22

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Wegener’s granulomatosis (WG) is a multisystem autoimmune vasculitis of small to medium sized blood vessels. Etiology is unknown. Nectrotising granulomatous vasculitis with destruction of the walls and narrowing of the vessel lumen leads to disturbanses of appropriate organs function. Clasical WG includes symptoms of upper and lower respiratory tract and kidneys, but WG can affect any organ. In about 16-20% of patients subglottic stenosis (SGS) due to granulomatous inflammation and scarring occurs. Symptoms of SGS (dyspnea, voice change and cough) without other symptoms make difficulties with diagnosis. Laryngoscopy or bronchoscopy with biopsy of tracheal lesion allows to establish proper diagnosis. SGS can be poorly responsive to systemic therapy. Method introduced by Langford et al. to therapy-intratracheal dilatation and local injection of corticosteroids proved to be an effective treatment of SGS.

keywords:

Subglottis stenosis in Wegener’s granulomatosis

Elżbieta Wiatr

Wegener’s granulomatosis (WG), subglottis stenosis (SGS), intratracheal injection of corticosteroids