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ISSN: 1689-832X
Journal of Contemporary Brachytherapy
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5/2016
vol. 8
 
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abstract:
Case report

Successful treatment of a 67-year-old woman with urethral adenocarcinoma with the use of external beam radiotherapy and image guided adaptive interstitial brachytherapy

Jasmin Mujkanovic
,
Kari Tanderup
,
Mads Agerbæk
,
Ulla Bisgaard
,
Søren Høyer
,
Jacob Christian Lindegaard
,
Lars Fokdal

J Contemp Brachytherapy 2016; 8, 5: 434–437
DOI: https://doi.org/10.5114/jcb.2016.63461
Online publish date: 2016/11/07
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Primary urethral cancer (PUC) is a very rare disease. This case report illustrates a successful treatment approach of a 67-year-old woman with a urethral adenocarcinoma selected for an organ preserving treatment with external beam radiotherapy (EBRT) and interstitial brachytherapy (BT) boost, using the GEC-ESTRO target concept originally designed for locally advanced cervical cancer (LACC). Treatment included EBRT with 45 Gy in 25 fractions followed by image guided adaptive interstitial BT (IGABT) with a pulsed-dose-rate (PDR) BT boost with 30 Gy in 50 hourly pulses. The D90 for CTVHR was 79.1 Gy in EQD23. At 24 months follow-up, the patient was recurrence free and without treatment related side effects.
keywords:

interstitial brachytherapy, primary urethral cancer, radiotherapy

  
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