eISSN: 1644-4124
ISSN: 1426-3912
Central European Journal of Immunology
Current issue Archive Manuscripts accepted About the journal Special Issues Editorial board Abstracting and indexing Subscription Contact Instructions for authors Ethical standards and procedures
Editorial System
Submit your Manuscript
SCImago Journal & Country Rank
2/2012
vol. 37
 
Share:
Share:
abstract:

Clinical immunology
Salivary interleukin-1β and Streptococcus mutans level in oral cavity

Sylwia Małgorzata Słotwińska
,
Marzanna Zaleska

(Centr Eur J Immunol 2012; 37 (2): 151-153)
Online publish date: 2012/05/22
View full text Get citation
 
Many studies have revealed correlation between serum or salivary immunoglobulin concentration and the progress of caries. Pathogens residing in the oral cavity can stimulate immune cells to produce cytokines. Antibacterial cellular reaction of T-cells in course of caries is related to the expression of superficial antigens of Streptococcus mutans. Interleukin-1β (IL-1β) – one of the most important cytokines in the human immune system – plays pivotal role in the anti-bacterial defense system. The aim of the presented study was to assess the IL-1β level in saliva, as well as to evaluate the Streptococcus mutans prevalence in the oral cavity. The statistical analysis of results revealed a relevant correlation between salivary IL-1β concentration and Streptococcus mutans level in oral cavity, thus suggesting the IL-1 significance in caries etiopathogenesis or denoting the modulation of cytokine concentration by bacterial antigens.
keywords:

dental caries, Streptococcus mutans, host response, interleukin-1β

Quick links
© 2024 Termedia Sp. z o.o.
Developed by Bentus.