A case of COVID-19 infection in a child with a tailored treatment strategy for Philadelphia chromosome-positive B-cell acute lymphoblastic leukaemia

Nataliia Luchyshyn; Nataliia Bodnarchuk-Sokhatska

doi:10.5114/pm.2025.152660

eISSN: 2081-2833
ISSN: 2081-0016

Medycyna Paliatywna/Palliative Medicine

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2/2025
vol. 17

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Opis przypadku

A case of COVID-19 infection in a child with a tailored treatment strategy for Philadelphia chromosome-positive B-cell acute lymphoblastic leukaemia

Nataliia Luchyshyn

¹

,

Nataliia Bodnarchuk-Sokhatska

¹

Department of Paediatrics №2, Ivan Horbachevsky Ternopil National Medical University of the Ministry of Health of Ukraine, Ternopil, Ukraine

Medycyna Paliatywna 2025; 17(2): 111–114

DOI: https://doi.org/10.5114/pm.2025.152660

Data publikacji online: 2025/07/10

Pełna treść artykułu Pobierz cytowanie

Metryki PlumX:

Children with acute lymphoblastic leukaemia (ALL) undergoing chemotherapy are at high risk for infection due to their immunocompromised status. To date, the effect of SARS-CoV-2 on leukaemia patients is known to be variable with a generally favourable clinical course. However, therapy-related toxicity and concomitant COVID-19 manifestations may influence decision-making in each individual case. We report the case of a 13-year-old boy diagnosed with acute Philadelphia chromosome-positive B-cell ALL who experienced multiple adverse events during intensive modified and deviated chemotherapy and COVID-19 infection. The aim of the study was to demonstrate that children receiving chemotherapy should be regularly screened for SARS-CoV-2 infection in the context of the ongoing global threat of COVID-19. Because there is no standard approach to chemotherapy modification, the management of coexisting ALL and COVID-19 in paediatric patients should be individualised.

A case of COVID-19 infection in a child with a tailored treatment strategy for Philadelphia chromosome-positive B-cell acute lymphoblastic leukaemia

Nataliia Luchyshyn 1 , Nataliia Bodnarchuk-Sokhatska 1

Nataliia Luchyshyn

¹

,

Nataliia Bodnarchuk-Sokhatska

¹