ISSN: 1734-1922
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Acute management of ACS
The role of the percutaneous coronary intervention in acute coronary syndrome

Freek W.A. Verheugt

Arch Med Sci 2010; 6, 1A: S 25–S 28
Online publish date: 2010/01/26
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Most cases of acute coronary syndromes are caused by coronary thrombosis on top of an atherosclerotic plaque. Besides intensive antithrombotic therapy, dilatation of the culprit lesion has now been standard of care. Sealing and stenting of the culprit lesion may prevent recurrent coronary thromboses, but also carries a risk of thromboembolic and atheroembolic complications. Furthermore, percutaneous coronary intervention after acute coronary syndrome needs even more intense antithrombotic therapy, which may further increase the risk of bleeding in general and the need for transfusion in particular, which is associated with increased risk of early and late mortality. Yet, percutaneous coronary intervention is necessary in many patients and in most of them it leads to a definitive solution of a coronary plaque rupture that lead to the acute coronary syndrome.

acute coronary syndrome, angina, complications, percutaneous coronary intervention

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