Analysis of nitric oxide concentration in peripheral blood in patients with lutein supplementation in different doses

Purpose
Comparison of nitric oxide concentration before and after lutein supplementation.

Material and methods
The study involved 54 people, aged 20-77 years, who were divided into 3 groups. Each group was taking lutein in a different dose for 3 months - 8 mg, 10 mg or 12 mg/day. The material for the study was venous blood collected before and after lutein supplementation. The concentration of nitric oxide (NO) in blood plasma was determined before and after 3 months of supplementation.

Results
After 3-month period of lutein supplementation, a statistically insignificant increase of nitric oxide concentration in plasma was observed in all studied groups. The highest increase was observed in the group taking 12 mg of lutein. The lowest was obtained in the supplement group of 10 mg of lutein.

Conclusions
The studied doses of lutein did not show any significant influence on the concentration of nitrites/nitrates in plasma in the studied groups. However, a tendency to increase the concentration of the tested compounds after the use of lutein in the dose of 12 mg was observed.