eISSN: 1644-4124
ISSN: 1426-3912
Central European Journal of Immunology
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vol. 27

Angiocentric lymphoma – its differentiation with the metastatic lung tumours

Andrzej Rojowski
Janusz Milanowski
Marek Michnar
Paweł Krawczyk

Online publish date: 2003/12/19


Angiocentric T-cell lymphoma (described by Liebow as lymphomatoid granulomatosis), which typically involves nose and upper respiratory system, is mostly a multisystemic disease. We report a 27-year-old patient with multiple lesions in both lungs in chest X-ray and CT images resembling the metastatic tumour of the lung. The immunophenotype of 74,5% of T-lymphocytes from BALF was CD3+, CD4-, CD8+, CD45RO+, CD56-, and CD4/CD8 ratio had a value of 0,26. The diagnosis of angiocentric lymphoma in this patient was confirmed by a histopatological analysis of the material from thoracotomy. The patient was treated with aggressive, multidrug chemotherapy, but he died 3 months after the beginning of the disease with the symptoms of the DIC syndrome and respiratory insufficiency.

angiocentric lymphoma, T-lymphocytes, lung neoplasms

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