Biological drugs in the treatment of atopic dermatitis –
current recommendations of the Polish Dermatological
Society, the Polish Society of Allergology, the Polish Pediatric
Society and the Polish Society of Family Medicine

Roman Nowicki; Magdalena Trzeciak; Lidia Rudnicka; Jacek Szepietowski; Marek Kulus; Maciej Kupczyk; Agnieszka Mastalerz-Migas; Jarosław Peregud-Pogorzelski; Karina Jahnz-Różyk; Joanna Narbutt; Magdalena Czarnecka-Operacz; Rafał Czajkowski; Elżbieta Grubska-Suchanek; Dorota Krasowska; Beata Kręcisz; Cezary Kowalewski; Aleksandra Lesiak; Malgorzata Olszewska; Zbigniew Samochocki; Radosław Śpiewak; Aleksandra Wilkowska

doi:10.5114/ada.2020.100496

eISSN: 2299-0046
ISSN: 1642-395X

Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii

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abstract:

Special paper

Biological drugs in the treatment of atopic dermatitis – current recommendations of the Polish Dermatological Society, the Polish Society of Allergology, the Polish Pediatric Society and the Polish Society of Family Medicine

Roman J. Nowicki

¹

,

Magdalena Trzeciak

¹

,

Lidia Rudnicka

²

,

Jacek Szepietowski

³

,

Marek Kulus

⁴

,

Maciej Kupczyk

⁵

,

Agnieszka Mastalerz-Migas

⁶

,

Jarosław Peregud-Pogorzelski

⁷

,

Karina Jahnz-Różyk

⁸

,

Joanna Narbutt

⁹

,

Magdalena Czarnecka-Operacz

¹⁰

,

Rafał Czajkowski

¹¹

,

Elżbieta Grubska-Suchanek

¹

,

Dorota Krasowska

¹²

,

Beata Kręcisz

¹³

,

Cezary Kowalewski

¹⁴

,

Aleksandra Lesiak

⁸

,

Malgorzata Olszewska

²

,

Zbigniew Samochocki

²

,

Radosław Śpiewak

¹⁵

,

Aleksandra Wilkowska

¹

Department of Dermatology, Venereology and Allergology, Medical University of Gdansk, Gdansk, Poland

Department of Dermatology, Medical University of Warsaw, Warsaw, Poland

Department of Dermatology, Venereology and Allergology, Medical University of Wroclaw, Wroclaw, Poland

Department of Pediatric Pneumonology and Allergology, Medical University of Warsaw, Warsaw, Poland

Department of Internal Medicine, Asthma and Allergy, Medical University of Lodz, Lodz, Poland

Department of Family Medicine, Medical University of Wroclaw, Wroclaw, Poland

Department of Pediatrics and Pediatric Oncology, Pomeranian Medical University, Szczecin, Poland

Department of Internal Medicine, Pneumonology, Allergology and Clinical Immunology, Military Medical Institute, Warsaw, Poland

Department of Dermatology, Pediatric and Oncological Dermatology, Medical University of Lodz, Lodz, Poland

10.

Department of Dermatology, Poznan University of Medical Sciences, Poznan, Poland

11.

Lodz, Poland Department of Dermatology and Venereology, “Ludwik Rydygier” Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University inTorun, Poland

12.

Department of Dermatology, Venereology and Pediatric Dermatology, Medical University of Lublin, Lublin, Poland

13.

Department of Dermatology, Faculty of Medicine and Health Sciences, Jan Kochanowski University, Kielce, Poland

14.

Department of Dermatology and Immunodermatology, Medical University of Warsaw, Warsaw, Poland

15.

Department of Experimental Dermatology and Cosmetology, Jagiellonian University Medical College, Krakow, Poland

Adv Dermatol Allergol 2020; XXXVII (5): 617-624

DOI: https://doi.org/10.5114/ada.2020.100496

Online publish date: 2020/11/07

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AMA

Nowicki RJ, Trzeciak M, Rudnicka L, et al. Biological drugs in the treatment of atopic dermatitis –
current recommendations of the Polish Dermatological
Society, the Polish Society of Allergology, the Polish Pediatric
Society and the Polish Society of Family Medicine. Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii. 2020;37(5):617-624. doi:10.5114/ada.2020.100496.

APA

Nowicki, R. J., Trzeciak, M., Rudnicka, L., Szepietowski, J., Kulus, M.,  & Kupczyk, M. et al. (2020). Biological drugs in the treatment of atopic dermatitis –
current recommendations of the Polish Dermatological
Society, the Polish Society of Allergology, the Polish Pediatric
Society and the Polish Society of Family Medicine. Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii, 37(5), 617-624. https://doi.org/10.5114/ada.2020.100496

Chicago

Nowicki, Roman J, Magdalena Trzeciak, Lidia Rudnicka, Jacek Szepietowski, Marek Kulus, Maciej Kupczyk,  and Agnieszka Mastalerz-Migas et al. 2020. "Biological drugs in the treatment of atopic dermatitis –
current recommendations of the Polish Dermatological
Society, the Polish Society of Allergology, the Polish Pediatric
Society and the Polish Society of Family Medicine". Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii 37 (5): 617-624. doi:10.5114/ada.2020.100496.

Harvard

Nowicki, R., Trzeciak, M., Rudnicka, L., Szepietowski, J., Kulus, M., Kupczyk, M., Mastalerz-Migas, A., Peregud-Pogorzelski, J., Jahnz-Różyk, K., Narbutt, J., Czarnecka-Operacz, M., Czajkowski, R., Grubska-Suchanek, E., Krasowska, D., Kręcisz, B., Kowalewski, C., Lesiak, A., Olszewska, M., Samochocki, Z., Śpiewak, R.,  and Wilkowska, A. (2020). Biological drugs in the treatment of atopic dermatitis –
current recommendations of the Polish Dermatological
Society, the Polish Society of Allergology, the Polish Pediatric
Society and the Polish Society of Family Medicine. Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii, 37(5), pp.617-624. https://doi.org/10.5114/ada.2020.100496

MLA

Nowicki, Roman et al. "Biological drugs in the treatment of atopic dermatitis –
current recommendations of the Polish Dermatological
Society, the Polish Society of Allergology, the Polish Pediatric
Society and the Polish Society of Family Medicine." Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii, vol. 37, no. 5, 2020, pp. 617-624. doi:10.5114/ada.2020.100496.

Vancouver

Nowicki R, Trzeciak M, Rudnicka L, Szepietowski J, Kulus M, Kupczyk M et al. Biological drugs in the treatment of atopic dermatitis –
current recommendations of the Polish Dermatological
Society, the Polish Society of Allergology, the Polish Pediatric
Society and the Polish Society of Family Medicine. Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii. 2020;37(5):617-624. doi:10.5114/ada.2020.100496.

Atopic dermatitis (AD) is secondary to genetic, immunological and microbiological disorders as well as epidermal barrier defects, which are the main targets of therapy. The disease proceeds with periodic exacerbations. Its development and course are influenced by numerous environmental and individual factors. In recent decades, in industrialized countries, there has been a threefold increase in the incidence of AD. There is also an increasing number of cases resistant to topical treatment. Effective treatment of AD should provide control of clinical symptoms, prevent exacerbations and improve the quality of life of patients. The multifactorial etiopathogenesis and various endotypes and phenotypes of AD justify the tendency to optimize and personalize the therapy. Currently, we recommend the use of dupilumab for the treatment of patients from 12 years of age with moderate and severe atopic dermatitis, who do not respond to topical treatment.

keywords:

Biological drugs in the treatment of atopic dermatitis – current recommendations of the Polish Dermatological Society, the Polish Society of Allergology, the Polish Pediatric Society and the Polish Society of Family Medicine

biological drugs, dupilumab, atopic dermatitis, therapeutic recommendations