Bisphosphonate – related osteonecrosis of the jaws

Maria Panaś; Małgorzata Zaleska; Paweł Pełka

eISSN: 2084-9834
ISSN: 0034-6233

Reumatologia/Rheumatology

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3/2010
vol. 48

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abstract:

Case report

Bisphosphonate – related osteonecrosis of the jaws

Maria Panaś

,

Małgorzata Zaleska

,

Paweł Pełka

Reumatologia 2010; 48, 3: 198–203

Online publish date: 2010/07/02

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Bisphosphonate therapy recommended for osteopenic diseases may lead to bone necrosis, particularly of the jaw bones. Until now, no case of any other bone necrosis related to bisphosphonate therapy has been documented. Clinical and radiological features of the necrosis as well as methods of treatment are presented. Moreover, three cases of female patients with bisphosphonate – related mandible necrosis are presented. In two of them, bisphosphonate therapy was administered because of metastatic spread of breast cancer to the vertebral column, and in one because of the osteoporosis. Before initiation of bisphosphonate therapy, sanitation of oral cavity is required followed by the high level of oral hygiene care.

keywords:

bisphosphonates, osteonecrosis of the jaws, osteoporosis, malignant bone metastasis

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BOOKS/KSIĄŻKI

Bisphosphonate – related osteonecrosis of the jaws

Maria Panaś , Małgorzata Zaleska , Paweł Pełka

bisphosphonates, osteonecrosis of the jaws, osteoporosis, malignant bone metastasis

Maria Panaś

,

Małgorzata Zaleska

,

Paweł Pełka